| Literature DB >> 9603893 |
F Molina1, A Jiménez-Sánchez, E C Guzmán.
Abstract
Changes of thymidine concentration in the growth medium affect the chromosome replication time of Thy- strains without at the same time causing a detectable difference in the growth rate (R. H. Pritchard and A. Zaritsky, Nature 226:126-131, 1970). Consequently, the optimal thymidine concentration cannot be determined by ascertaining which concentration produces the highest growth rate. Here we present a method for determining the optimal thymidine concentration of any Thy- Escherichia coli strain. Using this method, we found that the E. coli "wild-type" strain MG1655 has a partial Thy- phenotype.Entities:
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Year: 1998 PMID: 9603893 PMCID: PMC107270
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490