Literature DB >> 9599272

Dragmacidins: new protein phosphatase inhibitors from a southern australian deep-water marine sponge, spongosorites sp

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Abstract

A Spongosorites sp. collected during trawling operations off the southern coast of Australia returned the new alkaloid dragmacidin E (3), the structure of which was secured by detailed spectroscopic analysis. Dragmacidin E (3), and its co-metabolite dragmacidin D (1) have been identified as potent inhibitors of serine-threonine protein phosphatases.

Entities:  

Year:  1998        PMID： 9599272     DOI： 10.1021/np970483t

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  20 in total

1.  Total synthesis of (±)-dragmacidin E.

Authors:  Ken S Feldman; Paiboon Ngernmeesri
Journal:  Org Lett       Date:  2011-09-29       Impact factor: 6.005

2.  Synthesis of 2-Aminoazoles from Thioesters via α-Heterosubstituted Ketones by Copper-Mediated Cross-Coupling.

Authors:  Hiroyuki Kobayashi; John A Eickhoff; Armen Zakarian
Journal:  J Org Chem       Date:  2015-09-29       Impact factor: 4.354

3.  A strategy for the total synthesis of dragmacidin E. Construction of the core ring system.

Authors:  Raymond J Huntley; Raymond L Funk
Journal:  Org Lett       Date:  2006-10-12       Impact factor: 6.005

Review 4.  Life in cellulose houses: symbiotic bacterial biosynthesis of ascidian drugs and drug leads.

Authors:  Eric W Schmidt; Mohamed S Donia
Journal:  Curr Opin Biotechnol       Date:  2010-11-01       Impact factor: 9.740

5.  Syntheses of Cyclic Guanidine-Containing Natural Products.

Authors:  Yuyong Ma; Saptarshi De; Chuo Chen
Journal:  Tetrahedron       Date:  2015-02-25       Impact factor: 2.457

6.  Total Synthesis of (±)-Dragmacidin E: Problems Solved and Lessons Learned.

Authors:  Ken S Feldman; Paiboon Ngernmeesri
Journal:  Synlett       Date:  2012-08       Impact factor: 2.454

7.  Asymmetric hydrovinylation of vinylindoles. A facile route to cyclopenta[g]indole natural products (+)-cis-trikentrin A and (+)-cis-trikentrin B.

Authors:  Wang Liu; Hwan Jung Lim; T V RajanBabu
Journal:  J Am Chem Soc       Date:  2012-03-13       Impact factor: 15.419

8.  10-Step Asymmetric Total Synthesis and Stereochemical Elucidation of (+)-Dragmacidin D.

Authors:  Jeffrey J Jackson; Hiroyuki Kobayashi; Sophia D Steffens; Armen Zakarian
Journal:  Angew Chem Int Ed Engl       Date:  2015-06-30       Impact factor: 15.336

9.  Synthesis of Bisheteroarylalkanes by Heteroarylboration: Development and Application of a Pyridylidene-Copper Complex.

Authors:  Yuan Huang; M Kevin Brown
Journal:  Angew Chem Int Ed Engl       Date:  2019-03-27       Impact factor: 15.336

10.  Halogenated cyclic peptides isolated from the sponge Corticium sp.

Authors:  Damian W Laird; Daniel V LaBarbera; Xidong Feng; Tim S Bugni; Mary Kay Harper; Chris M Ireland
Journal:  J Nat Prod       Date:  2007-03-29       Impact factor: 4.050
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