Literature DB >> 9598490

An analysis of 653 trials of penile vibratory stimulation in men with spinal cord injury.

N L Brackett1, S M Ferrell, T C Aballa, M J Amador, O F Padron, J Sonksen, C M Lynne.   

Abstract

PURPOSE: We evaluated ejaculatory response and semen quality in 653 trials of penile vibratory stimulation in 211 men with spinal cord injury, and compared results with low versus high amplitude vibratory stimulation.
MATERIALS AND METHODS: Low and/or high amplitude penile vibratory stimulation was performed 1 to 27 times in each patient, and antegrade and retrograde specimens of those who ejaculated were analyzed.
RESULTS: Significantly more patients ejaculated using high (54.5%) versus low (39.9%) amplitude stimulation. Using either amplitude the ejaculatory success rate was highest in men with injuries at C3 to C7, followed by T1 to T5, T6 to T10 and T11 to L3. While high amplitude stimulation increased the ejaculatory success rate in each group, the highest rate occurred in men with injuries at C3 to C7 (65.6%). Ejaculation was reliable, since most men who ejaculated did so during 100% of the trials and within 2 minutes of stimulation onset. Symptoms of autonomic dysreflexia were safely managed with nifedipine. All patients who ejaculated produced antegrade specimens. With the exception of ejaculate volume, which was significantly higher with high versus low amplitude stimulation, semen parameters were similar using both vibrator amplitudes.
CONCLUSIONS: Ejaculatory success is better while semen quality is similar using high versus low amplitude penile vibratory stimulation in men with spinal cord injury. This method may be considered first line treatment for anejaculation in men with spinal cord injury due to its safety, relative effectiveness, and relatively low investment of time and money.

Entities:  

Mesh:

Year:  1998        PMID: 9598490

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  25 in total

Review 1.  Spinal cord control of ejaculation.

Authors:  Julien Allard; William A Truitt; Kevin E McKenna; Lique M Coolen
Journal:  World J Urol       Date:  2005-06-10       Impact factor: 4.226

2.  Measurement of sexual functioning after spinal cord injury: preferred instruments.

Authors:  Marcalee Sipski Alexander; Nancy L Brackett; Donald Bodner; Stacy Elliott; Amie Jackson; Jens Sonksen
Journal:  J Spinal Cord Med       Date:  2009       Impact factor: 1.985

Review 3.  A step-wise approach to sperm retrieval in men with neurogenic anejaculation.

Authors:  Mikkel Fode; Dana A Ohl; Jens Sønksen
Journal:  Nat Rev Urol       Date:  2015-10-20       Impact factor: 14.432

4.  Chronic Spinal Cord Injury Reduces Gastrin-Releasing Peptide in the Spinal Ejaculation Generator in Male Rats.

Authors:  J Walker Wiggins; Natalie Kozyrev; Jonathan E Sledd; George G Wilson; Lique M Coolen
Journal:  J Neurotrauma       Date:  2019-07-10       Impact factor: 5.269

5.  Evidence of a new pattern of ejaculation in men with spinal cord injury: ejaculation dyssynergia and implications for fertility.

Authors:  J-M Soler; J G Previnaire; R Mieusset
Journal:  Spinal Cord       Date:  2016-06-21       Impact factor: 2.772

Review 6.  Male sexual dysfunction and infertility associated with neurological disorders.

Authors:  Mikkel Fode; Sheila Krogh-Jespersen; Nancy L Brackett; Dana A Ohl; Charles M Lynne; Jens Sønksen
Journal:  Asian J Androl       Date:  2011-12-05       Impact factor: 3.285

7.  Cardiovascular responses to vibrostimulation for sperm retrieval in men with spinal cord injury.

Authors:  Victoria Elizabeth Claydon; Stacy Lorraine Elliott; Andrew William Sheel; Andrei Krassioukov
Journal:  J Spinal Cord Med       Date:  2006       Impact factor: 1.985

8.  Changes in Gene Expression and Metabolism in the Testes of the Rat following Spinal Cord Injury.

Authors:  Ryan D Fortune; Raymond J Grill; Christine Beeton; Mark Tanner; Redwan Huq; David S Loose
Journal:  J Neurotrauma       Date:  2016-12-02       Impact factor: 5.269

9.  Midodrine in patients with spinal cord injury and anejaculation: A double-blind randomized placebo-controlled pilot study.

Authors:  Bernard E Leduc; Christine Fournier; Géraldine Jacquemin; Yves Lepage; Bernard Vinet; Pierre-Olivier Hétu; Miguel Chagnon
Journal:  J Spinal Cord Med       Date:  2014-06-26       Impact factor: 1.985

Review 10.  Disorders of ejaculation.

Authors:  E A Jannini; C Simonelli; A Lenzi
Journal:  J Endocrinol Invest       Date:  2002-12       Impact factor: 4.256

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