Literature DB >> 27324318

Evidence of a new pattern of ejaculation in men with spinal cord injury: ejaculation dyssynergia and implications for fertility.

J-M Soler1,2, J G Previnaire3, R Mieusset2.   

Abstract

OBJECTIVES: To describe the presence of sperm in the prostatic urethra as a stand-alone ejaculation entity and to assess its characteristics.
METHODS: Thirty-three patients with anejaculation during sexual stimulation were enroled. Penile vibratory stimulations were carried out following bladder catherization and instillation of a pink buffering medium (Ferticult). Two-step catheterisation was then performed: a catheter was inserted through the urethral sphincter into the prostatic urethra to aspirate its content, and then bladder catheterisation was performed to collect the Ferticult. The procedure was repeated in some patients after at least 1 week. The characteristics of the semen collected from each organ were analysed and compared.
RESULTS: A total of 42 trials were obtained from 22 patients. Sperms were found in the prostatic urethra in 21 samples (50%) from 12 patients (11 with spinal cord injury, 1 with diabetes). The colour of all 21 prostatic urethra sperm samples differed from the Ferticult. Sperm motility was greater in 8 samples, sperm count was higher in 10 and pH was different in 10, compared with the bladder samples. The higher overall quality of the sperm allowed cryopreservation in 10 prostatic urethra samples compared with only 5 bladder samples. Four of the five patients who underwent repeated trials had a reproducible pattern of prostatic urethra ejaculation.
CONCLUSION: The presence of sperm in the prostatic urethra most probably results from 'ejaculation dyssynergia', a lack of coordination between bladder neck and external sphincter. Sperm from the prostatic urethra should be systematically sought to improve the outcome of assisted reproduction.

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Mesh:

Year:  2016        PMID: 27324318     DOI: 10.1038/sc.2016.78

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


  19 in total

1.  Semen parameters in men with spinal cord injury: changes and aetiology.

Authors:  Mohamed N Momen; Ibrahim Fahmy; Medhat Amer; Mohamad Arafa; Wael Zohdy; Taha A Naser
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2.  Side effects of intradetrusor botulinum toxin injections on ejaculation and fertility in men with spinal cord injury: preliminary findings.

Authors:  Romain Caremel; Frédérique Courtois; Kathleen Charvier; Alain Ruffion; Nicolas Morel Journel
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3.  An analysis of 653 trials of penile vibratory stimulation in men with spinal cord injury.

Authors:  N L Brackett; S M Ferrell; T C Aballa; M J Amador; O F Padron; J Sonksen; C M Lynne
Journal:  J Urol       Date:  1998-06       Impact factor: 7.450

4.  Bladder neck incompetence in patients with spinal cord injury: significance of sympathetic skin response.

Authors:  B Rodic; A Curt; V Dietz; B Schurch
Journal:  J Urol       Date:  2000-04       Impact factor: 7.450

5.  Ejaculatory dysfunction in spinal cord injury men is suggestive of dyssynergic ejaculation.

Authors:  J M Soler; J G Previnaire
Journal:  Eur J Phys Rehabil Med       Date:  2011-12       Impact factor: 2.874

6.  Prostatic massage: a simple method of semen retrieval in men with spinal cord injury.

Authors:  Mohamed Mostafa Arafa; Wael Ahmed Zohdy; Rany Shamloul
Journal:  Int J Androl       Date:  2007-02-12

7.  Sphincteric events during penile vibratory ejaculation and electroejaculation in men with spinal cord injuries.

Authors:  J Sønksen; D A Ohl; G Wedemeyer
Journal:  J Urol       Date:  2001-02       Impact factor: 7.450

8.  Detrusor bladder neck dyssynergia revisited.

Authors:  B Schurch; K Yasuda; A B Rossier
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9.  Midodrine improves orgasm in spinal cord-injured men: the effects of autonomic stimulation.

Authors:  Jean Marc Soler; Jean Gabriel Previnaire; Pierre Plante; Pierre Denys; Emmanuel Chartier-Kastler
Journal:  J Sex Med       Date:  2008-04-15       Impact factor: 3.802

10.  Midodrine improves ejaculation in spinal cord injured men.

Authors:  J M Soler; J G Previnaire; P Plante; P Denys; E Chartier-Kastler
Journal:  J Urol       Date:  2007-09-17       Impact factor: 7.450

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  5 in total

Review 1.  Fertility and sexuality in the spinal cord injury patient.

Authors:  J T Stoffel; F Van der Aa; D Wittmann; S Yande; S Elliott
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2.  A Primary Care Provider's Guide to Sexual Health for Individuals With Spinal Cord Injury.

Authors:  Sigmund Hough; Colleen Clemency Cordes; Lance L Goetz; Angela Kuemmel; Jesse A Lieberman; Linda R Mona; Mitchell S Tepper; Jithin G Varghese
Journal:  Top Spinal Cord Inj Rehabil       Date:  2020

Review 3.  Improving Sexual Satisfaction in Persons with Spinal Cord Injuries: Collective Wisdom.

Authors:  Marcalee Alexander; Frédérique Courtois; Stacy Elliott; Mitchell Tepper
Journal:  Top Spinal Cord Inj Rehabil       Date:  2017

Review 4.  Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatment.

Authors:  Ibrahim A Abdel-Hamid; Omar I Ali
Journal:  World J Mens Health       Date:  2018-01       Impact factor: 5.400

5.  Diagnosis of Partial Retrograde Ejaculation in Non-Azoospermic Infertile Men with Low Semen Volume.

Authors:  Roger Mieusset; Marie Walschaerts; François Isus; Thierry Almont; Myriam Daudin; Safouane M Hamdi
Journal:  PLoS One       Date:  2017-01-06       Impact factor: 3.240

  5 in total

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