Literature DB >> 9593962

Melanocortin-4 receptor mRNA expression in the developing autonomic and central nervous systems.

K G Mountjoy1, J M Wild.   

Abstract

MC4-R mRNA expression was investigated in fetal rats (E14-E20) using in situ hybridisation. The autonomic nervous system showed the highest levels of MC4-R mRNA expression. In the spinal cord, dense signal was seen over the future intermediolateral cell column and dorsal horn. In the brain, MC4-R was expressed by E14 in diencephalon neuroepithelia, telencephalon, lamina terminalis and spinal trigeminal nucleus and was expressed by E19 throughout many regions of the brain. Copyright 1998 Elsevier Science B.V.

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Year:  1998        PMID： 9593962     DOI： 10.1016/s0165-3806(98)00015-7

Source DB:  PubMed          Journal:  Brain Res Dev Brain Res        ISSN： 0165-3806


  18 in total

1.  Region-specific differences in brain melanocortin receptors in rats of the lean phenotype.

Authors:  Charu Shukla; Steven L Britton; Lauren G Koch; Colleen M Novak
Journal:  Neuroreport       Date:  2012-07-11       Impact factor: 1.837

Review 2.  Synaptic changes induced by melanocortin signalling.

Authors:  Vanni Caruso; Malin C Lagerström; Pawel K Olszewski; Robert Fredriksson; Helgi B Schiöth
Journal:  Nat Rev Neurosci       Date:  2014-02       Impact factor: 34.870

Review 3.  Participation of the central melanocortin system in metabolic regulation and energy homeostasis.

Authors:  Jin Kwon Jeong; Jae Geun Kim; Byung Ju Lee
Journal:  Cell Mol Life Sci       Date:  2014-06-04       Impact factor: 9.261

Review 4.  Role of the brain melanocortins in blood pressure regulation.

Authors:  Jussara M do Carmo; Alexandre A da Silva; Zhen Wang; Taolin Fang; Nicola Aberdein; Cecilia E Perez de Lara; John E Hall
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2017-03-06       Impact factor: 5.187

5.  Antagonism of the melanocortin system reduces cold and mechanical allodynia in mononeuropathic rats.

Authors:  D H Vrinten; W H Gispen; G J Groen; R A Adan
Journal:  J Neurosci       Date:  2000-11-01       Impact factor: 6.167

6.  Activation of melanocortin receptors in the intermediolateral cell column of the upper thoracic cord elicits tachycardia in the rat.

Authors:  Masamitsu Iwasa; Kazumi Kawabe; Hreday N Sapru
Journal:  Am J Physiol Heart Circ Physiol       Date:  2013-07-05       Impact factor: 4.733

7.  Contribution of regional brain melanocortin receptor subtypes to elevated activity energy expenditure in lean, active rats.

Authors:  C Shukla; L G Koch; S L Britton; M Cai; V J Hruby; M Bednarek; C M Novak
Journal:  Neuroscience       Date:  2015-09-25       Impact factor: 3.590

8.  Hypothalamic and hindbrain melanocortin receptors contribute to the feeding, thermogenic, and cardiovascular action of melanocortins.

Authors:  Karolina P Skibicka; Harvey J Grill
Journal:  Endocrinology       Date:  2009-10-23       Impact factor: 4.736

9.  Energetic responses are triggered by caudal brainstem melanocortin receptor stimulation and mediated by local sympathetic effector circuits.

Authors:  Karolina P Skibicka; Harvey J Grill
Journal:  Endocrinology       Date:  2008-03-27       Impact factor: 4.736

10.  Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes.

Authors:  Dorit P Zobel; Camilla H Andreasen; Niels Grarup; Hans Eiberg; Thorkild I A Sørensen; Annelli Sandbaek; Torsten Lauritzen; Knut Borch-Johnsen; Torben Jørgensen; Oluf Pedersen; Torben Hansen
Journal:  Diabetes       Date:  2008-12-10       Impact factor: 9.461
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