| Literature DB >> 9582196 |
M Rhodes1, R Straw, S Fernando, A Evans, T Lacey, A Dearlove, J Greystrong, J Walker, P Watson, P Weston, M Kelly, D Taylor, K Gibson, C Mundy, F Bourgade, C Poirier, D Simon, A L Brunialti, X Montagutelli, J L Gu'enet, A Haynes, S D Brown.
Abstract
The European Collaborative Interspecific Backcross (EUCIB) resource was constructed for the purposes of high-resolution genetic mapping of the mouse genome (). The large Mus spretus/C57BL/6 backcross of 982 progeny has a genetic resolution of 0.3 cM at the 95% confidence level ( approximately 500 kb in the mouse genome). We have used the EUCIB mapping resource to develop a genome-wide high-resolution genetic map incorporating 3368 microsatellites. The microsatellites are distributed among 2302 genetically separated bins with 1.46 markers per bin on average. Average bin separation is 0.61 cM. This high-resolution genetic map will aid the construction of a robust physical map of the mouse genome.Entities:
Mesh:
Substances:
Year: 1998 PMID: 9582196 DOI: 10.1101/gr.8.5.531
Source DB: PubMed Journal: Genome Res ISSN: 1088-9051 Impact factor: 9.043