Literature DB >> 9579855

Drug delivery and targeting.

R Langer1.   

Abstract

When a pharmaceutical agent is encapsulated within, or attached to, a polymer or lipid, drug safety and efficacy can be greatly improved and new therapies are possible. This has provided the impetus for active study of the design of degradable materials, intelligent delivery systems and approaches for delivery through different portals in the body.

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Year:  1998        PMID： 9579855

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  358 in total

1.  Improvement of in vitro and in vivo antileishmanial activities of 2', 6'-dihydroxy-4'-methoxychalcone by entrapment in poly(D,L-lactide) nanoparticles.

Authors:  E C Torres-Santos; J M Rodrigues; D L Moreira; M A Kaplan; B Rossi-Bergmann
Journal:  Antimicrob Agents Chemother       Date:  1999-07       Impact factor: 5.191

Review 2.  Optimisation of treatment by applying programmable rate-controlled drug delivery technology.

Authors:  Yie W Chien; Senshang Lin
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

3.  Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy.

Authors:  Nagesh Kolishetti; Shanta Dhar; Pedro M Valencia; Lucy Q Lin; Rohit Karnik; Stephen J Lippard; Robert Langer; Omid C Farokhzad
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-04       Impact factor: 11.205

4.  Patterning osteogenesis by inducible gene expression in microfluidic culture systems.

Authors:  Yue Zhang; Zulma Gazit; Gadi Pelled; Dan Gazit; Gordana Vunjak-Novakovic
Journal:  Integr Biol (Camb)       Date:  2010-10-05       Impact factor: 2.192

Review 5.  Bone marrow-targeted liposomal carriers.

Authors:  Keitaro Sou; Beth Goins; Babatunde O Oyajobi; Bruno L Travi; William T Phillips
Journal:  Expert Opin Drug Deliv       Date:  2011-01-31       Impact factor: 6.648

Review 6.  Hyaluronic acid-based nanocarriers for intracellular targeting: interfacial interactions with proteins in cancer.

Authors:  Ki Young Choi; Gurusamy Saravanakumar; Jae Hyung Park; Kinam Park
Journal:  Colloids Surf B Biointerfaces       Date:  2011-10-20       Impact factor: 5.268

7.  Leukocyte-inspired biodegradable particles that selectively and avidly adhere to inflamed endothelium in vitro and in vivo.

Authors:  Harshad S Sakhalkar; Milind K Dalal; Aliasger K Salem; Ramin Ansari; Jie Fu; Mohammad F Kiani; David T Kurjiaka; Justin Hanes; Kevin M Shakesheff; Douglas J Goetz
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-10       Impact factor: 11.205

8.  Precise control of PLG microsphere size provides enhanced control of drug release rate.

Authors:  Cory Berkland; Martin King; Amanda Cox; Kyekyoon Kim; Daniel W Pack
Journal:  J Control Release       Date:  2002-07-18       Impact factor: 9.776

9.  Porous nanoparticle supported lipid bilayers (protocells) as delivery vehicles.

Authors:  Juewen Liu; Alison Stace-Naughton; Xingmao Jiang; C Jeffrey Brinker
Journal:  J Am Chem Soc       Date:  2009-02-04       Impact factor: 15.419

Review 10.  Biomaterials and stem cells for tissue engineering.

Authors:  Zhanpeng Zhang; Melanie J Gupte; Peter X Ma
Journal:  Expert Opin Biol Ther       Date:  2013-01-17       Impact factor: 4.388
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