Literature DB >> 10390243

Improvement of in vitro and in vivo antileishmanial activities of 2', 6'-dihydroxy-4'-methoxychalcone by entrapment in poly(D,L-lactide) nanoparticles.

E C Torres-Santos1, J M Rodrigues, D L Moreira, M A Kaplan, B Rossi-Bergmann.   

Abstract

The inhibition of intracellular Leishmania amazonensis growth by 2', 6'-dihydroxy-4'-methoxychalcone (DMC) isolated from Piper aduncum was further enhanced after encapsulation of DMC in polymeric nanoparticles. Encapsulated DMC also showed increased antileishmanial activity in infected BALB/c mice, as evidenced by significantly smaller lesions and fewer parasites in the lesions.

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Year:  1999        PMID： 10390243      PMCID： PMC89364     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  19 in total

1.  Selective effect of 2',6'-dihydroxy-4'-methoxychalcone isolated from Piper aduncum on Leishmania amazonensis.

Authors:  E C Torres-Santos; D L Moreira; M A Kaplan; M N Meirelles; B Rossi-Bergmann
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

Review 2.  Leishmaniasis. Public health aspects and control.

Authors:  P Desjeux
Journal:  Clin Dermatol       Date:  1996 Sep-Oct       Impact factor: 3.541

3.  Activity of liposomal amphotericin B against experimental cutaneous leishmaniasis.

Authors:  V Yardley; S L Croft
Journal:  Antimicrob Agents Chemother       Date:  1997-04       Impact factor: 5.191

Review 4.  Human leishmaniasis: clinical, diagnostic, and chemotherapeutic developments in the last 10 years.

Authors:  J D Berman
Journal:  Clin Infect Dis       Date:  1997-04       Impact factor: 9.079

5.  In vivo and in vitro localization of Leishmania within macrophage phagolysosomes: use of colloidal gold as a lysosomal label.

Authors:  J D Berman; T B Fioretti; D M Dwyer
Journal:  J Protozool       Date:  1981-05

6.  The activity and ultrastructural localization of primaquine-loaded poly (d,l-lactide) nanoparticles in Leishmania donovani infected mice.

Authors:  J M Rodrigues; S L Croft; H Fessi; C Bories; J P Devissaguet
Journal:  Trop Med Parasitol       Date:  1994-09

7.  Visceral leishmaniasis: rapid response to AmBisome treatment.

Authors:  O P Smith; I M Hann; H Cox; V Novelli
Journal:  Arch Dis Child       Date:  1995-08       Impact factor: 3.791

8.  Liposomal amphotericin B (AmBisome) in the treatment of complicated kala-azar under field conditions.

Authors:  J Seaman; C Boer; R Wilkinson; J de Jong; E de Wilde; E Sondorp; R Davidson
Journal:  Clin Infect Dis       Date:  1995-07       Impact factor: 9.079

9.  Body distribution of fully biodegradable [14C]-poly(lactic acid) nanoparticles coated with albumin after parenteral administration to rats.

Authors:  D V Bazile; C Ropert; P Huve; T Verrecchia; M Marlard; A Frydman; M Veillard; G Spenlehauer
Journal:  Biomaterials       Date:  1992       Impact factor: 12.479

10.  Transfer of zymosan (yeast cell walls) to the parasitophorous vacuoles of macrophages infected with Leishmania amazonensis.

Authors:  P S Veras; C de Chastellier; M Rabinovitch
Journal:  J Exp Med       Date:  1992-09-01       Impact factor: 14.307
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  10 in total

Review 1.  Potential of Piper spp. as a source of new compounds for the leishmaniases treatment.

Authors:  Juliana Figueiredo Peixoto; Ygor Jessé Ramos; Davyson de Lima Moreira; Carlos Roberto Alves; Luiz Filipe Gonçalves-Oliveira
Journal:  Parasitol Res       Date:  2021-07-10       Impact factor: 2.289

2.  Activity of synthetic chalcones in hamsters experimentally infected with Leishmania (Viannia) braziliensis.

Authors:  Tatiane F P de Mello; Bruna M Cardoso; Sara N Lopes; Heriberto R Bitencourt; Evandra M Voltarelli; Luzmarina Hernandes; Sandra M A Aristides; Maria V C Lonardoni; Thais G V Silveira
Journal:  Parasitol Res       Date:  2015-06-23       Impact factor: 2.289

3.  Altered sterol profile induced in Leishmania amazonensis by a natural dihydroxymethoxylated chalcone.

Authors:  Eduardo Caio Torres-Santos; Maria Isabel Sampaio-Santos; Frederick S Buckner; Kohei Yokoyama; Michael Gelb; Julio A Urbina; Bartira Rossi-Bergmann
Journal:  J Antimicrob Chemother       Date:  2009-01-28       Impact factor: 5.790

4.  Depot Subcutaneous Injection with Chalcone CH8-Loaded Poly(Lactic-Co-Glycolic Acid) Microspheres as a Single-Dose Treatment of Cutaneous Leishmaniasis.

Authors:  Ariane de Jesus Sousa-Batista; Wallace Pacienza-Lima; Natalia Arruda-Costa; Camila Alves Bandeira Falcão; Maria Ines Ré; Bartira Rossi-Bergmann
Journal:  Antimicrob Agents Chemother       Date:  2018-02-23       Impact factor: 5.191

5.  Novel Arsenic Nanoparticles Are More Effective and Less Toxic than As (III) to Inhibit Extracellular and Intracellular Proliferation of Leishmania donovani.

Authors:  Sudipta Chakraborty; Kaushik Bhar; Sandip Saha; Rajarshi Chakrabarti; Anjali Pal; Anirban Siddhanta
Journal:  J Parasitol Res       Date:  2014-12-31

Review 6.  The Role of Natural Products in Drug Discovery and Development against Neglected Tropical Diseases.

Authors:  Peter Mubanga Cheuka; Godfrey Mayoka; Peggoty Mutai; Kelly Chibale
Journal:  Molecules       Date:  2016-12-31       Impact factor: 4.411

7.  Dietary Vitamin D3 Deficiency Increases Resistance to Leishmania (Leishmania) amazonensis Infection in Mice.

Authors:  Izabella Pereira da Silva Bezerra; Gabriel Oliveira-Silva; Danielle Sophia Ferreira Santos Braga; Mirian França de Mello; Juliana Elena Silveira Pratti; Joyce Carvalho Pereira; Alessandra Marcia da Fonseca-Martins; Luan Firmino-Cruz; Diogo Maciel-Oliveira; Tadeu Diniz Ramos; André Macedo Vale; Daniel Claudio Oliveira Gomes; Bartira Rossi-Bergmann; Herbert Leonel de Matos Guedes
Journal:  Front Cell Infect Microbiol       Date:  2019-04-09       Impact factor: 5.293

8.  An investigation of the antileishmanial properties of semi-synthetic saponins.

Authors:  Orlagh Anderson; Joseph Beckett; Carla C Briggs; Liam A Natrass; Charles F Cranston; Elizabeth J Wilkinson; Jack H Owen; Rhodri Mir Williams; Angelos Loukaidis; Marc E Bouillon; Deiniol Pritchard; Martina Lahmann; Mark S Baird; Paul W Denny
Journal:  RSC Med Chem       Date:  2020-06-09

9.  In Vitro Antiparasitic and Apoptotic Effects of Antimony Sulfide Nanoparticles on Leishmania infantum.

Authors:  Saied Soflaei; Abdolhossein Dalimi; Fatemeh Ghaffarifar; Mojtaba Shakibaie; Ahmad Reza Shahverdi; Mohsen Shafiepour
Journal:  J Parasitol Res       Date:  2012-06-26

10.  Immunotherapy using anti-PD-1 and anti-PD-L1 in Leishmania amazonensis-infected BALB/c mice reduce parasite load.

Authors:  Alessandra M da Fonseca-Martins; Tadeu D Ramos; Juliana E S Pratti; Luan Firmino-Cruz; Daniel Claudio Oliveira Gomes; Lynn Soong; Elvira M Saraiva; Herbert L de Matos Guedes
Journal:  Sci Rep       Date:  2019-12-30       Impact factor: 4.379
  10 in total

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