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Literature DB >> 957483

7-Methyl-guanosine and efficiency of RNA translation.

Abstract

Brome mosaic virus RNAs 3 and 4 were chemically modified to remove the terminal 7-methyl-guanosine (m7G) structure, and the modified RNAs were tested for their messenger activity in a cell-free system derived from wheat embryo. Amino acid incorporation and ribosome-binding data show that removal of m7G results in reduction, but not complete abolition, of the messenger activity of the RNA. This suggests that the function of m7G may be related to efficient translation of messenger RNA. Possible involvement of other structural factors in RNA translation is discussed.

Entities: Chemical Species

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Year: 1976 PMID： 957483 PMCID： PMC354898 DOI： 10.1128/JVI.19.2.637-642.1976

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

12 in total

1. Methylation-dependent translation of viral messenger RNAs in vitro.

Authors: G W Both; A K Banerjee; A J Shatkin
Journal: Proc Natl Acad Sci U S A Date: 1975-03 Impact factor: 11.205

2. 5'-Terminal 7-methylguanosine in eukaryotic mRNA is required for translation.

Authors: S Muthukrishnan; G W Both; Y Furuichi; A J Shatkin
Journal: Nature Date: 1975-05-01 Impact factor: 49.962

3. Blocked 5' termini in brome mosaic virus RNA.

Authors: R Dasgupta; F Harada; P Kaesberg
Journal: J Virol Date: 1976-04 Impact factor: 5.103

4. The modified 5'-terminal sequences in messenger RNA of mouse myeloma cells.

Authors: S Cory; J M Adams
Journal: J Mol Biol Date: 1975-12-25 Impact factor: 5.469

5. Translation of brome mosaic viral ribonucleic acid in a cell-free system derived from wheat embryo.

Authors: D S Shih; P Kaesberg
Journal: Proc Natl Acad Sci U S A Date: 1973-06 Impact factor: 11.205

6. Multiple genetic components in bromegrass mosaic virus.

Authors: L C Lane; P Kaesberg
Journal: Nat New Biol Date: 1971-07-14

7. A two-dimensional fractionation procedure for radioactive nucleotides.

Authors: F Sanger; G G Brownlee; B G Barrell
Journal: J Mol Biol Date: 1965-09 Impact factor: 5.469

8. mRNA methylation and protein synthesis in extracts from embryos of brine shrimp, Artemia salina.

Authors: S Muthukrishnan; W Filipowicz; J M Sierra; G W Both; A J Shatkin; S Ochoa
Journal: J Biol Chem Date: 1975-12-25 Impact factor: 5.157

9. Translation of virus mRNA: synthesis of bacteriophage Q beta proteins in a cell-free extract from wheat embryo.

Authors: J W Davies; P Kaesberg
Journal: J Virol Date: 1973-12 Impact factor: 5.103

10. Identical 3'-terminal octanucleotide sequence in 18S ribosomal ribonucleic acid from different eukaryotes. A proposed role for this sequence in the recognition of terminator codons.

Authors: J Shine; L Dalgarno
Journal: Biochem J Date: 1974-09 Impact factor: 3.857

10 in total

7-Methyl-guanosine and efficiency of RNA translation.

1. Methylation-dependent translation of viral messenger RNAs in vitro.

2. 5'-Terminal 7-methylguanosine in eukaryotic mRNA is required for translation.

3. Blocked 5' termini in brome mosaic virus RNA.

4. The modified 5'-terminal sequences in messenger RNA of mouse myeloma cells.

5. Translation of brome mosaic viral ribonucleic acid in a cell-free system derived from wheat embryo.

6. Multiple genetic components in bromegrass mosaic virus.

7. A two-dimensional fractionation procedure for radioactive nucleotides.

8. mRNA methylation and protein synthesis in extracts from embryos of brine shrimp, Artemia salina.

9. Translation of virus mRNA: synthesis of bacteriophage Q beta proteins in a cell-free extract from wheat embryo.

10. Identical 3'-terminal octanucleotide sequence in 18S ribosomal ribonucleic acid from different eukaryotes. A proposed role for this sequence in the recognition of terminator codons.

1. Removal of 5'-terminal m7G from eukaryotic mRNAs by potato nucleotide pyrophosphatase and its effect on translation.

2. 5'-Terminal 7-methylguanosine and mRNA function: influence of potassium concentration on translation in vitro.

3. S-adenosyl-L-homocysteine as a stimulator of viral RNA synthesis by two distinct cytoplasmic polyhedrosis viruses.

4. Isolation of polyribosomes and messenger RNA active in in vitro synthesis of soybean seed proteins.

Review 5. 5'-terminal cap structure in eucaryotic messenger ribonucleic acids.

6. Specific inhibition of capped mRNA translation in vitro by m7G5'pppp5'G and m7G5'pppp5'm7G.

7. Reovirus-induced modification of cap-dependent translation in infected L cells.

8. Sequence of an oligonucleotide derived from the 3' end of each of the four brome mosaic viral RNAs.

9. Loss of infectivity of brome mosaic virus RNA after chemical modification of the 3' or 5' terminus.

10. tRNA-like structures of plant viral RNAs: conformational requirements for adenylation and aminoacylation.