A A Moon-Fanelli1, N H Dodman. 1. Department of Clinical Sciences, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA.
Abstract
OBJECTIVE: To identify factors associated with onset and continued elicitation of tail chasing in Bull Terriers and other terriers and to determine response to treatment with clomipramine hydrochloride, a serotonin-reuptake inhibitor. DESIGN: Prospective study. ANIMALS: 18 tail-chasing terriers (15 Bull Terriers, 1 Miniature Bull Terrier, 1 American Staffordshire Terrier, 1 Jack Russell Terrier). PROCEDURE: 5 dogs were evaluated for tail chasing by a veterinarian at the behavior clinic of the veterinary teaching hospital and 13 dogs were evaluated by the owner's local veterinarian, who confirmed the diagnosis and treated the dog. It was recommended that all dogs in the study be given clomipramine orally at a dosage of 1 to 2 mg/kg (0.5 to 0.9 mg/lb) of body weight, every 12 hours. RESULTS: Of the 18 dogs, 15 were treated with clomipramine within the recommended dosage range, and 3 dogs required treatment at a slightly higher dosage range to control tail chasing. After 1 to 12 weeks of treatment, 9 of 12 (75%) dogs were reported to have a 75% or greater improvement (reduction) in tail chasing. CLINICAL IMPLICATIONS: Findings of this study may aid in recognition and treatment of compulsive tail chasing. In conjunction with appropriate management changes, clomipramine administration appears to be an effective treatment for this otherwise refractory condition.
OBJECTIVE: To identify factors associated with onset and continued elicitation of tail chasing in Bull Terriers and other terriers and to determine response to treatment with clomipramine hydrochloride, a serotonin-reuptake inhibitor. DESIGN: Prospective study. ANIMALS: 18 tail-chasing terriers (15 Bull Terriers, 1 Miniature Bull Terrier, 1 American Staffordshire Terrier, 1 Jack Russell Terrier). PROCEDURE: 5 dogs were evaluated for tail chasing by a veterinarian at the behavior clinic of the veterinary teaching hospital and 13 dogs were evaluated by the owner's local veterinarian, who confirmed the diagnosis and treated the dog. It was recommended that all dogs in the study be given clomipramine orally at a dosage of 1 to 2 mg/kg (0.5 to 0.9 mg/lb) of body weight, every 12 hours. RESULTS: Of the 18 dogs, 15 were treated with clomipramine within the recommended dosage range, and 3 dogs required treatment at a slightly higher dosage range to control tail chasing. After 1 to 12 weeks of treatment, 9 of 12 (75%) dogs were reported to have a 75% or greater improvement (reduction) in tail chasing. CLINICAL IMPLICATIONS: Findings of this study may aid in recognition and treatment of compulsive tail chasing. In conjunction with appropriate management changes, clomipramine administration appears to be an effective treatment for this otherwise refractory condition.
Authors: Katriina Tiira; Osmo Hakosalo; Lauri Kareinen; Anne Thomas; Anna Hielm-Björkman; Catherine Escriou; Paul Arnold; Hannes Lohi Journal: PLoS One Date: 2012-07-26 Impact factor: 3.240