Literature DB >> 956654

Antibody-induced killing in vivo of L1210/MTX-R cells quantitated in passively immunized mice with 131I-iododeoxyuridine-labeled cells and whole-body measurement of retained radioactivity.

G A Carlson, G Terres.   

Abstract

The killing of the LR subline of the DBA/2J leukemia L1210/MTX by passive antibody was followed in vivo with 131I-iododeoxyuridine-labeled cells and whole-body measurement of retained radioactivity. The in vivo killing of LR cells was proportional to the in vitro 2-mercaptoethanol resistant titer, independent of the complement system, and radioresistant. Although a large percentage of the leukemic cells was killed in passively immunized mice, the protective effect of the passive antiserum was dependent on the active immune response of the host.

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Year:  1976        PMID： 956654

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  6 in total

1.  Lysis of uninfected and virus-infected cells in vivo: a rejection mechanism in addition to that mediated by natural killer cells.

Authors:  C A Biron; S Habu; K Okumura; R M Welsh
Journal:  J Virol       Date:  1984-06       Impact factor: 5.103

2.  Pregnant mice are not primed but can be primed to fetal alloantigens.

Authors:  T G Wegmann; C A Waters; D W Drell; G A Carlson
Journal:  Proc Natl Acad Sci U S A       Date:  1979-05       Impact factor: 11.205

3.  Proceedings of the British Association For Cancer Research, 19th Annual General Meeting St. Edmund Hall, University of Oxford 4--6 April, 1978.

Authors: 
Journal:  Br J Cancer       Date:  1978-07       Impact factor: 7.640

4.  Significance of cytotoxic lymphocytes after various immunizing procedures in a virus-induced non-producer syngeneic system: correlation between in vitro and in vivo lytic activity.

Authors:  Y Pioch; M Gerber; B Serrou
Journal:  Br J Cancer       Date:  1980-08       Impact factor: 7.640

5.  Antigenic modulation of Friend virus erythroleukemic cells in vitro by serum from mice with dormant erythroleukemia.

Authors:  E V Genovesi; P A Marx; E F Wheelock
Journal:  J Exp Med       Date:  1977-08-01       Impact factor: 14.307

6.  Allogeneic tumor rejection induced by the intravenous injection of Lyt-2+ cytolytic T lymphocyte clones.

Authors:  H D Engers; A L Glasebrook; G D Sorenson
Journal:  J Exp Med       Date:  1982-10-01       Impact factor: 14.307
  6 in total

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