| Literature DB >> 9566415 |
G P Pizzolato1, R Sztajzel, K Burkhardt, M Megret, B Borisch.
Abstract
The immunosuppressive agent FK 506 is widely used in liver transplant patients. Neurotoxicity is a major complication of its use. We report progressive and irreversible neurologic complications occurring in a 39-year-old woman who underwent liver transplantation and was treated with FK 506. Neuropathologic examination revealed multiple vasculitic lesions. The possibility of an FK 506-mediated toxic effect on the cerebral vessels is suggested.Entities:
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Year: 1998 PMID: 9566415 DOI: 10.1212/wnl.50.4.1154
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910