Literature DB >> 15221068

[Case of inflammatory vasculopathy and encephalopathy caused by treatment with tacrolimus].

Adrian Ringelstein1, Katja Bongs, Burkhard Sorge-Hädicke, Peter Berlit.   

Abstract

The case of inflammatory vasculopathy and encephalopathy caused by treatment with tacrolimus is reported. This 49-year-old woman developed progressive gait ataxia and right-sided hemiparesis after 7 years of tacrolimus therapy for focal sclerosing glomerulonephritis. MRI presented multifocal cerebral lesions with contrast enhancement. Oligoclonal banding was positive. When the treatment with tacrolimus was stopped, the clinical symptoms resolved completely and the MRI findings improved with corticoid monotherapy.

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Year:  2005        PMID： 15221068     DOI： 10.1007/s00115-004-1744-1

Source DB:  PubMed          Journal:  Nervenarzt        ISSN： 0028-2804            Impact factor:   1.214


  8 in total

1.  Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.

Authors:  C Cordon-Cardo; J P O'Brien; D Casals; L Rittman-Grauer; J L Biedler; M R Melamed; J R Bertino
Journal:  Proc Natl Acad Sci U S A       Date:  1989-01       Impact factor: 11.205

2.  Cerebral vasculitis during FK 506 treatment in a liver transplant patient.

Authors:  G P Pizzolato; R Sztajzel; K Burkhardt; M Megret; B Borisch
Journal:  Neurology       Date:  1998-04       Impact factor: 9.910

Review 3.  Neurotoxicity of immunosuppressive drugs.

Authors:  E F Wijdicks
Journal:  Liver Transpl       Date:  2001-11       Impact factor: 5.799

4.  Inhibition of the multidrug efflux pump in isolated hepatocyte couplets by immunosuppressants FK506 and cyclosporine.

Authors:  N Takeguchi; K Ichimura; M Koike; W Matsui; T Kashiwagura; K Kawahara
Journal:  Transplantation       Date:  1993-03       Impact factor: 4.939

5.  Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein.

Authors:  A Tsuji; I Tamai; A Sakata; Y Tenda; T Terasaki
Journal:  Biochem Pharmacol       Date:  1993-09-14       Impact factor: 5.858

6.  Central nervous system toxicity after liver transplantation. The role of cyclosporine and cholesterol.

Authors:  P C de Groen; A J Aksamit; J Rakela; G S Forbes; R A Krom
Journal:  N Engl J Med       Date:  1987-10-01       Impact factor: 91.245

7.  A reversible posterior leukoencephalopathy syndrome.

Authors:  J Hinchey; C Chaves; B Appignani; J Breen; L Pao; A Wang; M S Pessin; C Lamy; J L Mas; L R Caplan
Journal:  N Engl J Med       Date:  1996-02-22       Impact factor: 91.245

8.  [Diagnosis and differential cerebral vasculitis diagnosis].

Authors:  P Berlit
Journal:  Nervenarzt       Date:  2004-02       Impact factor: 1.214
  8 in total
  2 in total

Review 1.  Drug-induced cerebellar ataxia: a systematic review.

Authors:  J van Gaalen; F G Kerstens; R P P W M Maas; L Härmark; B P C van de Warrenburg
Journal:  CNS Drugs       Date:  2014-12       Impact factor: 5.749

2.  Primary central nervous system vasculitis: clinical experiences with 21 new European cases.

Authors:  Markus Kraemer; Peter Berlit
Journal:  Rheumatol Int       Date:  2009-12-19       Impact factor: 2.631
  2 in total

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