Literature DB >> 9542955

Detection of JC virus in cerebrospinal fluid (CSF) samples from patients with progressive multifocal leukoencephalopathy but not in CSF samples from patients with herpes simplex encephalitis, enteroviral meningitis, or multiple sclerosis.

G Bogdanovic1, P Priftakis, A L Hammarin, M Söderström, A Samuelson, I Lewensohn-Fuchs, T Dalianis.   

Abstract

JC virus (JCV) DNA was detected in cerebrospinal fluid (CSF) samples from patients with progressive multifocal leukoencephalopathy (PML) but not in CSF samples from patients with herpes simplex encephalitis, enteroviral meningitis, or multiple sclerosis. This suggests that inflammatory processes in the brain do not necessarily reactivate JCV, which further supports the proposal that the presence of JCV DNA in the CSF is diagnostic for PML.

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Year:  1998        PMID： 9542955      PMCID： PMC104707          DOI： 10.1128/JCM.36.4.1137-1138.1998

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  17 in total

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Authors:  I W Fong; C B Britton; K E Luinstra; E Toma; J B Mahony
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7.  Analysis of PCR as a tool for detection of JC virus DNA in cerebrospinal fluid for diagnosis of progressive multifocal leukoencephalopathy.

Authors:  A L Hammarin; G Bogdanovic; V Svedhem; R Pirskanen; L Morfeldt; M Grandien
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5.  A globally applicable PCR-based detection and discrimination of BK and JC polyomaviruses.

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  5 in total

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