Literature DB >> 9541011

Molecular cloning and characterization of two novel transport proteins from rat kidney.

E Schömig1, F Spitzenberger, M Engelhardt, F Martel, N Ording, D Gründemann.   

Abstract

The recent cloning of renal transport systems for organic anions and cations (OAT1, OCT1, and OCT2) opened the possibility to search, via polymerase chain reaction (PCR) homology screening, for novel transport proteins. Two integral membrane proteins, UST1 and UST2, were cloned from rat kidney. RT-PCR revealed that UST1 is confined to the kidney whereas UST2 mRNA was detected in all tested tissues. Sequence analyses suggest that UST1 and UST2, together with four related transporters, comprise, within the major facilitator superfamily, a so far unrecognized transporter family, termed amphiphilic solute facilitator (ASF) family. Characteristic signatures for the ASF family were identified.

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Year:  1998        PMID： 9541011     DOI： 10.1016/s0014-5793(98)00203-8

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  14 in total

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Review 3.  The role of glia in stress: polyamines and brain disorders.

Authors:  Serguei N Skatchkov; Michel A Woodbury-Fariña; Misty Eaton
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4.  Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells.

Authors:  Dirk Gründemann; Ann-Cathrin Koschker; Christine Haag; Cornelius Honold; Tim Zimmermann; Edgar Schömig
Journal:  Br J Pharmacol       Date:  2002-11       Impact factor: 8.739

5.  Discovery of the ergothioneine transporter.

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6.  Are organic cation transporters capable of transporting prostaglandins?

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7.  A three-dimensional model of human organic anion transporter 1: aromatic amino acids required for substrate transport.

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Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2006-07-20       Impact factor: 3.619

9.  Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models.

Authors:  D H Sweet; S A Eraly; D A Vaughn; K T Bush; S K Nigam
Journal:  Kidney Int       Date:  2006-03       Impact factor: 10.612

10.  Activation of liver X receptor inhibits OCT2-mediated organic cation transport in renal proximal tubular cells.

Authors:  Teerasak Wongwan; Suticha Kittayaruksakul; Nithi Asavapanumas; Varanuj Chatsudthipong; Sunhapas Soodvilai
Journal:  Pflugers Arch       Date:  2017-07-25       Impact factor: 3.657
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