Literature DB >> 9538691

An atlas of serpin conformations.

J Whisstock1, R Skinner, A M Lesk.   

Abstract

The serpins are a family of proteins that inhibit chymotrypsin-like serine proteinases, with an unusual mechanism involving a large conformational change known as the stressed-->relaxed (S-->R) transition. This article is a guide to the known serpin conformations and their biological significance.

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Year:  1998        PMID： 9538691     DOI： 10.1016/s0968-0004(97)01172-9

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  27 in total

1.  Predicting conformational switches in proteins.

Authors:  M Young; K Kirshenbaum; K A Dill; S Highsmith
Journal:  Protein Sci       Date:  1999-09       Impact factor: 6.725

2.  Effect of protease-activated receptor (PAR)-1, -2 and -4-activating peptides, thrombin and trypsin in rat isolated airways.

Authors:  J M Chow; J D Moffatt; T M Cocks
Journal:  Br J Pharmacol       Date:  2000-12       Impact factor: 8.739

3.  Crystal structure of baculovirus P35: role of a novel reactive site loop in apoptotic caspase inhibition.

Authors:  A J Fisher; W d Cruz; S J Zoog; C L Schneider; P D Friesen
Journal:  EMBO J       Date:  1999-04-15       Impact factor: 11.598

4.  The role of strand 1 of the C beta-sheet in the structure and function of alpha(1)-antitrypsin.

Authors:  S P Bottomley; I D Lawrenson; D Tew; W Dai; J C Whisstock; R N Pike
Journal:  Protein Sci       Date:  2001-12       Impact factor: 6.725

5.  Modulation of protein-protein interactions by synthetic receptors: design of molecules that disrupt serine protease-proteinaceous inhibitor interaction.

Authors:  Hyung Soon Park; Qing Lin; Andrew D Hamilton
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-16       Impact factor: 11.205

6.  Probing the serpin structural-transition mechanism in ovalbumin mutant R339T by proteolytic-cleavage kinetics of the reactive-centre loop.

Authors:  Yasuhiro Arii; Masaaki Hirose
Journal:  Biochem J       Date:  2002-04-15       Impact factor: 3.857

Review 7.  How do proteins avoid becoming too stable? Biophysical studies into metastable proteins.

Authors:  Lisa D Cabrita; Stephen P Bottomley
Journal:  Eur Biophys J       Date:  2003-09-19       Impact factor: 1.733

8.  Mutagenesis of the bovSERPINA3-3 demonstrates the requirement of aspartate-371 for intermolecular interaction and formation of dimers.

Authors:  X Blanchet; A Péré-Brissaud; N Duprat; E Pinault; D Delourme; A Ouali; C Combet; A Maftah; P Pélissier; L Brémaud
Journal:  Protein Sci       Date:  2012-05-18       Impact factor: 6.725

9.  Familial encephalopathy with neuroserpin inclusion bodies.

Authors:  R L Davis; P D Holohan; A E Shrimpton; A H Tatum; J Daucher; G H Collins; R Todd; C Bradshaw; P Kent; D Feiglin; A Rosenbaum; M S Yerby; C M Shaw; F Lacbawan; D A Lawrence
Journal:  Am J Pathol       Date:  1999-12       Impact factor: 4.307

10.  A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome.

Authors:  Theodoros Goulas; Miroslaw Ksiazek; Irene Garcia-Ferrer; Alicja M Sochaj-Gregorczyk; Irena Waligorska; Marcin Wasylewski; Jan Potempa; F Xavier Gomis-Rüth
Journal:  J Biol Chem       Date:  2017-05-16       Impact factor: 5.157
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