Literature DB >> 9537803

A single dose of methamphetamine in neonatal gerbils affects adult prefrontal gamma-aminobutyric acid innervation.

M Nossoll1, G Teuchert-Noodt, R R Dawirs.   

Abstract

A single non-invasive dose of methamphetamine (50 mg/kg i.p.) was administered to neonatal male gerbils (Meriones unguiculatus) aged 14 days. At the age of postnatal day 90, the gamma-aminobutyric acid (GABA) immunoreactive profiles were electron microscopically quantified in the prelimbic area of the prefrontal cortex and compared with those of saline-treated controls. This early solitary drug challenge resulted in adult GABAergic innervation densities which were approximately 40% above those of saline-treated controls.

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Year:  1997        PMID: 9537803

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  6 in total

1.  Isolation rearing or methamphetamine traumatisation induce a "dysconnection" of prefrontal efferents in gerbils: implications for schizophrenia.

Authors:  F Bagorda; G Teuchert-Noodt; K Lehmann
Journal:  J Neural Transm (Vienna)       Date:  2005-06-15       Impact factor: 3.575

2.  Developmental pattern changes of prefrontal efferents in the juvenile gerbil (Meriones unguiculatus).

Authors:  A V Witte; S Brummelte; G Teuchert-Noodt
Journal:  J Neural Transm (Vienna)       Date:  2007-06-08       Impact factor: 3.575

3.  Alteration in the GABAergic network of the prefrontal cortex in a potential animal model of psychosis.

Authors:  S Brummelte; J Neddens; G Teuchert-Noodt
Journal:  J Neural Transm (Vienna)       Date:  2007-01-03       Impact factor: 3.575

4.  The maturation of the acetylcholine system in the dentate gyrus of gerbils (Meriones unguiculatus) is affected by epigenetic factors.

Authors:  A Busche; A Bagorda; K Lehmann; J Neddens; G Teuchert-Noodt
Journal:  J Neural Transm (Vienna)       Date:  2005-06-15       Impact factor: 3.575

5.  A simulation model for compensatory plasticity in the prefrontal cortex inducing a cortico-cortical dysconnection in early brain development.

Authors:  M Butz; G Teuchert-Noodt
Journal:  J Neural Transm (Vienna)       Date:  2006-02-06       Impact factor: 3.850

6.  Long-term effects of a single adult methamphetamine challenge: minor impact on dopamine fibre density in limbic brain areas of gerbils.

Authors:  Susanne Brummelte; Thorsten Grund; Andrea Czok; Gertraud Teuchert-Noodt; Jörg Neddens
Journal:  Behav Brain Funct       Date:  2006-03-28       Impact factor: 3.759

  6 in total

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