| Literature DB >> 9529610 |
J Tschopp1, M Thome, K Hofmann, E Meinl.
Abstract
The induction of apoptosis of virus-infected cells is an important host defense mechanism against invading pathogens. Some viruses express anti-apoptotic proteins that efficiently block apoptosis induced by death receptors or in response to stress signaled through mitochondria. Viral interference with host cell apoptosis leads to enhanced viral replication and may promote cancer.Entities:
Mesh:
Substances:
Year: 1998 PMID: 9529610 DOI: 10.1016/s0959-437x(98)80066-x
Source DB: PubMed Journal: Curr Opin Genet Dev ISSN: 0959-437X Impact factor: 5.578