Literature DB >> 10634210

A portrait of the Bcl-2 protein family: life, death, and the whole picture.

M Pellegrini1, A Strasser.   

Abstract

The Bcl-2 family of proteins are important regulators of cell death. They are comprised of two opposing factions, the proapoptotic versus the antiapoptotic members. Both are required for normal development and cellular homeostasis of the immune system and other tissues. However, in certain circumstances they may participate in the development of disease.

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Year:  1999        PMID： 10634210     DOI： 10.1023/a:1020598632068

Source DB:  PubMed          Journal:  J Clin Immunol        ISSN： 0271-9142            Impact factor:   8.317


  226 in total

Review 1.  Viruses and apoptosis.

Authors:  V O'Brien
Journal:  J Gen Virol       Date:  1998-08       Impact factor: 3.891

Review 2.  Caspases and caspase inhibitors.

Authors:  P Villa; S H Kaufmann; W C Earnshaw
Journal:  Trends Biochem Sci       Date:  1997-10       Impact factor: 13.807

3.  p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following gamma-irradiation.

Authors:  A R Clarke; S Gledhill; M L Hooper; C C Bird; A H Wyllie
Journal:  Oncogene       Date:  1994-06       Impact factor: 9.867

4.  bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death.

Authors:  L H Boise; M González-García; C E Postema; L Ding; T Lindsten; L A Turka; X Mao; G Nuñez; C B Thompson
Journal:  Cell       Date:  1993-08-27       Impact factor: 41.582

5.  Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death.

Authors:  M Dubois-Dauphin; H Frankowski; Y Tsujimoto; J Huarte; J C Martinou
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-12       Impact factor: 11.205

6.  Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain.

Authors:  J P MacManus; A M Buchan; I E Hill; I Rasquinha; E Preston
Journal:  Neurosci Lett       Date:  1993-12-24       Impact factor: 3.046

7.  Synergistic effects of caspase inhibitors and MK-801 in brain injury after transient focal cerebral ischaemia in mice.

Authors:  J Ma; M Endres; M A Moskowitz
Journal:  Br J Pharmacol       Date:  1998-06       Impact factor: 8.739

Review 8.  Insights from transgenic mice regarding the role of bcl-2 in normal and neoplastic lymphoid cells.

Authors:  S Cory; A W Harris; A Strasser
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1994-08-30       Impact factor: 6.237

9.  Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death.

Authors:  E Yang; J Zha; J Jockel; L H Boise; C B Thompson; S J Korsmeyer
Journal:  Cell       Date:  1995-01-27       Impact factor: 41.582

10.  Loss of Fas/Apo-1 receptor accelerates lymphomagenesis in E mu L-MYC transgenic mice but not in animals infected with MoMuLV.

Authors:  M Zörnig; A Grzeschiczek; M B Kowalski; K U Hartmann; T Möröy
Journal:  Oncogene       Date:  1995-06-15       Impact factor: 9.867
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Authors:  Pouyan E Boukany; Andrew Morss; Wei-Ching Liao; Brian Henslee; Hyunchul Jung; Xulang Zhang; Bo Yu; Xinmei Wang; Yun Wu; Lei Li; Keliang Gao; Xin Hu; Xi Zhao; O Hemminger; Wu Lu; Gregory P Lafyatis; L James Lee
Journal:  Nat Nanotechnol       Date:  2011-10-16       Impact factor: 39.213

2.  Mechanisms of apoptosis of T-cells in human tuberculosis.

Authors:  Christina S Hirsch; John L Johnson; Alphonse Okwera; Richard A Kanost; Mianda Wu; Pierre Peters; Mathew Muhumuza; Harriet Mayanja-Kizza; Roy D Mugerwa; Peter Mugyenyi; Jerrold J Ellner; Zahra Toossi
Journal:  J Clin Immunol       Date:  2005-07       Impact factor: 8.317

3.  Rifampicin inhibits CD95-mediated apoptosis of Jurkat T cells via glucocorticoid receptors by modifying the expression of molecules regulating apoptosis.

Authors:  Rama Yerramasetti; Sastry Gollapudi; Sudhir Gupta
Journal:  J Clin Immunol       Date:  2002-01       Impact factor: 8.317

Review 4.  Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's disease: many pathways to neurodegeneration.

Authors:  D Allan Butterfield; Sarita S Hardas; Miranda L Bader Lange
Journal:  J Alzheimers Dis       Date:  2010       Impact factor: 4.472

5.  Molecular basis of rifampicin-induced inhibition of anti-CD95-induced apoptosis of peripheral blood T lymphocytes: the role of CD95 ligand and FLIPs.

Authors:  Sastry Gollapudi; Suman Jaidka; Sudhir Gupta
Journal:  J Clin Immunol       Date:  2003-01       Impact factor: 8.317

Review 6.  Bioconjugation of oligonucleotides for treating liver fibrosis.

Authors:  Zhaoyang Ye; Houssam S Hajj Houssein; Ram I Mahato
Journal:  Oligonucleotides       Date:  2007

7.  Spinal cord decompression reduces rat neural cell apoptosis secondary to spinal cord injury.

Authors:  Kan Xu; Qi-xin Chen; Fang-cai Li; Wei-shan Chen; Min Lin; Qiong-hua Wu
Journal:  J Zhejiang Univ Sci B       Date:  2009-03       Impact factor: 3.066

8.  Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease.

Authors:  Miranda L Bader Lange; Giovanna Cenini; Marta Piroddi; Hafiz Mohmmad Abdul; Rukhsana Sultana; Francesco Galli; Maurizio Memo; D Allan Butterfield
Journal:  Neurobiol Dis       Date:  2007-11-12       Impact factor: 5.996

Review 9.  Molecular therapy for hepatic injury and fibrosis: where are we?

Authors:  Colette C Prosser; Roy D Yen; Jian Wu
Journal:  World J Gastroenterol       Date:  2006-01-28       Impact factor: 5.742

10.  Malignant and tuberculous pleural effusions: immunophenotypic cellular characterization.

Authors:  Lucia Maria Zanatta de Aguiar; Leila Antonangelo; Francisco S Vargas; Maria Cláudia Nogueira Zerbini; Maria Mirtes Sales; David E Uip; Paulo Hilário Nascimento Saldiva
Journal:  Clinics (Sao Paulo)       Date:  2008-10       Impact factor: 2.365
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