Literature DB >> 9527806

Effects of aluminum hydroxide and famotidine on bioavailability of tosufloxacin in healthy volunteers.

R Minami1, C Nakamura, N Inotsume, M Nakano.   

Abstract

This study was designed to determine the influence of aluminum hydroxide and famotidine on the bioavailability of tosufloxacin. Coadministration of aluminum hydroxide reduced the bioavailability of tosufloxacin by 31.6% (P < 0.05). Famotidine did not alter tosufloxacin absorption. To avoid potential treatment failures, the concurrent use of tosufloxacin and aluminum hydroxide should be avoided altogether.

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Year:  1998        PMID： 9527806      PMCID： PMC105434          DOI： 10.1128/AAC.42.2.453

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  8 in total

1.  Effect of antacid medication on the pharmacokinetics of temafloxacin.

Authors:  G R Granneman; U Stephan; B Birner; F Sörgel; D Mukherjee
Journal:  Clin Pharmacokinet       Date:  1992       Impact factor: 6.447

2.  The relationship between gastric emptying of semisolids and paracetamol absorption.

Authors:  O U Petring; B Adelhøj; M Ibsen; H E Poulsen
Journal:  Br J Clin Pharmacol       Date:  1986-12       Impact factor: 4.335

3.  A pharmacokinetic analysis program (multi) for microcomputer.

Authors:  K Yamaoka; Y Tanigawara; T Nakagawa; T Uno
Journal:  J Pharmacobiodyn       Date:  1981-11

4.  Interactions of aluminum, magnesium, and calcium ions with nalidixic acid.

Authors:  M Nakano; M Yamamoto; T Arita
Journal:  Chem Pharm Bull (Tokyo)       Date:  1978-05       Impact factor: 1.645

5.  Effects of aluminum and magnesium antacids and ranitidine on the absorption of ciprofloxacin.

Authors:  D E Nix; W A Watson; M E Lener; R W Frost; G Krol; H Goldstein; J Lettieri; J J Schentag
Journal:  Clin Pharmacol Ther       Date:  1989-12       Impact factor: 6.875

6.  Effect of antacid on absorption of the quinolone lomefloxacin.

Authors:  J Shimada; K Shiba; T Oguma; H Miwa; Y Yoshimura; T Nishikawa; Y Okabayashi; T Kitagawa; S Yamamoto
Journal:  Antimicrob Agents Chemother       Date:  1992-06       Impact factor: 5.191

7.  The effect of ferrous sulphate on the absorption of norfloxacin, ciprofloxacin and ofloxacin.

Authors:  P Lehto; K T Kivistö; P J Neuvonen
Journal:  Br J Clin Pharmacol       Date:  1994-01       Impact factor: 4.335

8.  Different effects of products containing metal ions on the absorption of lomefloxacin.

Authors:  P Lehto; K T Kivistö
Journal:  Clin Pharmacol Ther       Date:  1994-11       Impact factor: 6.875
  8 in total
  3 in total

Review 1.  Clinically significant drug interactions with antacids: an update.

Authors:  Ryuichi Ogawa; Hirotoshi Echizen
Journal:  Drugs       Date:  2011-10-01       Impact factor: 9.546

Review 2.  Pharmacokinetics and pharmacodynamics of fluoroquinolones.

Authors:  J Turnidge
Journal:  Drugs       Date:  1999       Impact factor: 9.546

3.  Relationship of quantitative structure and pharmacokinetics in fluoroquinolone antibacterials.

Authors:  Die Cheng; Wei-Ren Xu; Chang-Xiao Liu
Journal:  World J Gastroenterol       Date:  2007-05-07       Impact factor: 5.742
  3 in total

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