Literature DB >> 9519808

Hypotensive effect of gamma-glutamylmethylamide in spontaneously hypertensive rats.

H Yokogoshi1, M Kobayashi.   

Abstract

The effect of gamma-glutamylmethylamide(GMA), one of the components of green tea extract, on the blood pressure in spontaneously hypertensive rats (SHR) was investigated. The effect of glutamic acid and r-glutamylethylamide (theanine), which is structurally similar to GMA, was also examined. When SHR were injected with glutamic acid (2000mg/kg), the blood pressure was not altered. The same dose of theanine decreased it significantly. GMA administration to SHR reduced the blood pressure significantly, and its degree of hypotensive action was more effective than that by theanine administration.

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Year:  1998        PMID： 9519808     DOI： 10.1016/s0024-3205(98)00029-0

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


  6 in total

1.  Effect of green tea (camellia sinensis l.) leaf extract on reproductive system of adult male albino rats.

Authors:  Shyamal Kanti Das; Soumendra Nath Karmakar
Journal:  Int J Physiol Pathophysiol Pharmacol       Date:  2015-12-25

2.  Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.

Authors:  Peter J Rogers; Jessica E Smith; Susan V Heatherley; C W Pleydell-Pearce
Journal:  Psychopharmacology (Berl)       Date:  2007-09-23       Impact factor: 4.530

3.  Can Tea Consumption be a Safe and Effective Therapy Against Diabetes Mellitus-Induced Neurodegeneration?

Authors:  Ana R Nunes; Marco G Alves; Paula I Moreira; Pedro F Oliveira; Branca M Silva
Journal:  Curr Neuropharmacol       Date:  2014-12       Impact factor: 7.363

Review 4.  Hypertension in Asian/Pacific Island Americans.

Authors:  Ralph E Watson; Rudruidee Karnchanasorn; Ved V Gossain
Journal:  J Clin Hypertens (Greenwich)       Date:  2009-03       Impact factor: 3.738

5.  Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses.

Authors:  Ai Yoto; Mao Motoki; Sato Murao; Hidehiko Yokogoshi
Journal:  J Physiol Anthropol       Date:  2012-10-29       Impact factor: 2.867

6.  Effect of l-theanine tablets in reducing stress-related emotional signs in cats: an open-label field study.

Authors:  V Dramard; L Kern; J Hofmans; C A Rème; C S Nicolas; V Chala; C Navarro
Journal:  Ir Vet J       Date:  2018-10-09       Impact factor: 2.146
  6 in total

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