| Literature DB >> 27073594 |
Shyamal Kanti Das1, Soumendra Nath Karmakar1.
Abstract
Green tea leaf extract (GTLE), used in this experiment has shown great influence on male reproductive system functionally as well as morphologically. The extract was prepared according to the method of Wei. H. et al. The extract was given to two different experimental animal groups with two different doses during 26 consecutive days. After treatment it was found that, the weight of the testis was markedly reduced instead of normal weight gain of all the animals. The sperm count and motility were reduced for the treated groups as compared with control animal group. The enzymes like SGPT and SGOT were as usual and other blood parameters like glucose and protein were also as usual comparing with controlled group. Testosterone level was reduced in the treated groups. FSH and LH levels were also altered accordingly in treated groups. Histological examination showed inhibition of spermatogenesis as evidenced by disintegration of seminiferous tubules of testis. Result of this study showed that GTLE has potent castrative effect on male reproductive system in dose dependent manner.Entities:
Keywords: 17β hydroxyl steroid dehydrogenase; Green tea leaf extract; castrative agent; catechin; epigallocatechin; sperm motility
Year: 2015 PMID: 27073594 PMCID: PMC4788727
Source DB: PubMed Journal: Int J Physiol Pathophysiol Pharmacol ISSN: 1944-8171