Literature DB >> 9519291

Helicases: a unifying structural theme?

L E Bird1, H S Subramanya, D B Wigley.   

Abstract

The recent structure determinations of PcrA DNA helicase, NS3 RNA helicase, and Rep DNA helicase have revealed similarities between their folds. When these data are examined with sequence and biochemical analyses, as well as microscopy studies of hexameric helicases, a picture of a unifying structure and mechanism for all helicases is beginning to emerge.

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Year:  1998        PMID: 9519291     DOI: 10.1016/s0959-440x(98)80004-3

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN: 0959-440X            Impact factor:   6.809


  52 in total

1.  Crystal structure of the DNA nucleotide excision repair enzyme UvrB from Thermus thermophilus.

Authors:  M Machius; L Henry; M Palnitkar; J Deisenhofer
Journal:  Proc Natl Acad Sci U S A       Date:  1999-10-12       Impact factor: 11.205

2.  Visualization of unwinding activity of duplex RNA by DbpA, a DEAD box helicase, at single-molecule resolution by atomic force microscopy.

Authors:  Arnon Henn; Ohad Medalia; Shu-Ping Shi; Michal Steinberg; Francois Franceschi; Irit Sagi
Journal:  Proc Natl Acad Sci U S A       Date:  2001-04-10       Impact factor: 11.205

Review 3.  Type I restriction systems: sophisticated molecular machines (a legacy of Bertani and Weigle).

Authors:  N E Murray
Journal:  Microbiol Mol Biol Rev       Date:  2000-06       Impact factor: 11.056

4.  The 100-kda U5 snRNP protein (hPrp28p) contacts the 5' splice site through its ATPase site.

Authors:  N Ismaïli; M Sha; E H Gustafson; M M Konarska
Journal:  RNA       Date:  2001-02       Impact factor: 4.942

5.  Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism.

Authors:  P Soultanas; M S Dillingham; P Wiley; M R Webb; D B Wigley
Journal:  EMBO J       Date:  2000-07-17       Impact factor: 11.598

6.  The human coronavirus 229E superfamily 1 helicase has RNA and DNA duplex-unwinding activities with 5'-to-3' polarity.

Authors:  A Seybert; A Hegyi; S G Siddell; J Ziebuhr
Journal:  RNA       Date:  2000-07       Impact factor: 4.942

7.  An mRNA degrading complex in Rhodobacter capsulatus.

Authors:  S Jäger; O Fuhrmann; C Heck; M Hebermehl; E Schiltz; R Rauhut; G Klug
Journal:  Nucleic Acids Res       Date:  2001-11-15       Impact factor: 16.971

Review 8.  Nucleoside triphosphate-dependent restriction enzymes.

Authors:  D T Dryden; N E Murray; D N Rao
Journal:  Nucleic Acids Res       Date:  2001-09-15       Impact factor: 16.971

Review 9.  Modularity and specialization in superfamily 1 and 2 helicases.

Authors:  Martin R Singleton; Dale B Wigley
Journal:  J Bacteriol       Date:  2002-04       Impact factor: 3.490

10.  Comparative genomics and evolution of proteins involved in RNA metabolism.

Authors:  Vivek Anantharaman; Eugene V Koonin; L Aravind
Journal:  Nucleic Acids Res       Date:  2002-04-01       Impact factor: 16.971

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