Literature DB >> 950261

The frequency of adverse drug reactions as dependent upon age, sex and duration of hospitalization.

U Klein, M Klein, H Sturm, M Rothenbühler, R Huber, P Stucki, I Gikalov, M Keller, R Hoigné.   

Abstract

In 1972, 171 (18, 7%) of 914 patients showed evidence of an adverse drug reaction (ADR) in a prospective study of the division of internal medicine in a regional teaching hospital (Zieglerspital, Bern). The following factors correlated positively with frequency of ADR: 1. The duration of hospital stay. 2. The age between 60 and 80 years. 3. Female sex. 4. Previous ADR. The fact that most of the ADR occur within the first three weeks of a hospital stay, combined with point 1, suggests early ADR having some predictive value for duration of hospital stay. Statistical data of type, severity, duration and pathogenesis of ADR are given. The drugs involved are mentioned.

Entities:  

Mesh:

Year:  1976        PMID: 950261

Source DB:  PubMed          Journal:  Int J Clin Pharmacol Biopharm        ISSN: 0340-0026


  16 in total

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6.  Pharmacokinetics of ciprofloxacin in the elderly: increased oral bioavailability and reduced renal clearance.

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Review 7.  Gender as a risk factor for adverse events to medications.

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Review 9.  Quinolone disposition in the elderly. Practical implications.

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10.  [Early detection and determination of the incidence of side effects in the hospital by intensive (comprehensive) drug monitoring].

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