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Literature DB >> 1392225

Adverse effects of antidepressants in the elderly.

Abstract

Depression is a common problem in old age and the use of antidepressant drugs is particularly prevalent among elderly patients. Limited data suggest that dose requirements may be lower in the elderly because of age-related changes in pharmacokinetics and perhaps also in sensitivity. The side effect profiles of the various antidepressants are reviewed with regard to their potential to cause specific problems in the older patients. Anticholinergic actions, orthostatic hypotension and sedative effects warrant particular care in the elderly.

Entities: Disease Species

Mesh：

Substances：
Antidepressive Agents

Year: 1992 PMID： 1392225 DOI： 10.2165/00002512-199202050-00008

Source DB: PubMed Journal: Drugs Aging ISSN： 1170-229X Impact factor: 3.923

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6 in total