Literature DB >> 9501212

Functional evidence for a nasopharyngeal carcinoma tumor suppressor gene that maps at chromosome 3p21.3.

Y Cheng1, N E Poulos, M L Lung, G Hampton, B Ou, M I Lerman, E J Stanbridge.   

Abstract

Nasopharyngeal carcinoma is a malignancy that is prevalent among populations from Southeast Asia. Epidemiological studies indicate that genetic predisposition, Epstein-Barr virus, and environmental conditions may play a role in determining incidence. Molecular studies have implicated a tumor suppressor gene(s) on the short arm of chromosome 3. In this study we provide functional evidence, via monochromosome transfer, for a tumor suppressor gene(s) activity in chromosome 3p21.3.

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Year:  1998        PMID： 9501212      PMCID： PMC19691          DOI： 10.1073/pnas.95.6.3042

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  42 in total

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Journal:  Science       Date:  1991-10-11       Impact factor: 47.728

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Journal:  Cytogenet Cell Genet       Date:  1996

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Journal:  Science       Date:  1987-04-10       Impact factor: 47.728

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Journal:  Cancer Res       Date:  1997-09-15       Impact factor: 12.701

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Journal:  Nature       Date:  1996-03-14       Impact factor: 49.962

8.  Establishment and characterization of two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected with Epstein-Barr virus and derived from nasopharyngeal carcinomas.

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Journal:  Int J Cancer       Date:  1990-01-15       Impact factor: 7.396

9.  A region of homozygous deletion on chromosome 9p21-22 in primary nasopharyngeal carcinoma.

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Journal:  Cancer Res       Date:  1994-08-01       Impact factor: 12.701

10.  Distinct 3p21.3 deletions in lung cancer and identification of a new human semaphorin.

Authors:  J Roche; F Boldog; M Robinson; L Robinson; M Varella-Garcia; M Swanton; B Waggoner; R Fishel; W Franklin; R Gemmill; H Drabkin
Journal:  Oncogene       Date:  1996-03-21       Impact factor: 9.867
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  23 in total

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Authors:  Merrin Man Long Leong; Arthur Kwok Leung Cheung; Wei Dai; Sai Wah Tsao; Chi Man Tsang; Christopher W Dawson; Josephine Mun Yee Ko; Maria Li Lung
Journal:  Proc Natl Acad Sci U S A       Date:  2019-06-24       Impact factor: 11.205

3.  Chromosome 14 transfer and functional studies identify a candidate tumor suppressor gene, mirror image polydactyly 1, in nasopharyngeal carcinoma.

Authors:  Arthur Kwok Leung Cheung; Hong Lok Lung; Josephine Mun Yee Ko; Yue Cheng; Eric J Stanbridge; Eugene R Zabarovsky; John M Nicholls; Daniel Chua; Sai Wah Tsao; Xin-Yuan Guan; Maria Li Lung
Journal:  Proc Natl Acad Sci U S A       Date:  2009-08-10       Impact factor: 11.205

4.  Extracellular protease ADAMTS9 suppresses esophageal and nasopharyngeal carcinoma tumor formation by inhibiting angiogenesis.

Authors:  Paulisally Hau Yi Lo; Hong Lok Lung; Arthur Kwok Leung Cheung; Suneel S Apte; Kwok Wah Chan; Fung Mei Kwong; Josephine Mun Yee Ko; Yue Cheng; Simon Law; Gopesh Srivastava; Eugene R Zabarovsky; Sai Wah Tsao; Johnny Cheuk On Tang; Eric J Stanbridge; Maria Li Lung
Journal:  Cancer Res       Date:  2010-06-15       Impact factor: 12.701

5.  Epstein-Barr virus-encoded LMP2A regulates viral and cellular gene expression by modulation of the NF-kappaB transcription factor pathway.

Authors:  Suzanne Stewart; Christopher W Dawson; Kenzo Takada; John Curnow; Cary A Moody; John W Sixbey; Lawrence S Young
Journal:  Proc Natl Acad Sci U S A       Date:  2004-10-21       Impact factor: 11.205

6.  Cloning and characterization of the NPCEDRG gene promoter.

Authors:  Defu Hou; Yongjun Guan; Jianping Liu; Zhefeng Xiao; Yongmei Ouyang; Yanhui Yu; Zhuchu Chen
Journal:  Mol Cell Biochem       Date:  2010-09-07       Impact factor: 3.396

7.  Frequent hypermethylation of RASSF1A and TSLC1, and high viral load of Epstein-Barr Virus DNA in nasopharyngeal carcinoma and matched tumor-adjacent tissues.

Authors:  Liang Zhou; Weihong Jiang; Caiping Ren; Zhihua Yin; Xiangling Feng; Weidong Liu; Qian Tao; Kaitai Yao
Journal:  Neoplasia       Date:  2005-09       Impact factor: 5.715

8.  Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma.

Authors:  Wei Dai; Hong Zheng; Arthur Kwok Leung Cheung; Clara Sze-man Tang; Josephine Mun Yee Ko; Bonnie Wing Yan Wong; Merrin Man Long Leong; Pak Chung Sham; Florence Cheung; Dora Lai-Wan Kwong; Roger Kai Cheong Ngan; Wai Tong Ng; Chun Chung Yau; Jianji Pan; Xun Peng; Stewart Tung; Zengfeng Zhang; Mingfang Ji; Alan Kwok-Shing Chiang; Anne Wing-Mui Lee; Victor Ho-Fun Lee; Ka-On Lam; Kwok Hung Au; Hoi Ching Cheng; Harry Ho-Yin Yiu; Maria Li Lung
Journal:  Proc Natl Acad Sci U S A       Date:  2016-03-07       Impact factor: 11.205

9.  Mutations in a gene encoding a midbody kelch protein in familial and sporadic classical Hodgkin lymphoma lead to binucleated cells.

Authors:  Stephen J Salipante; Matthew E Mealiffe; Jeremy Wechsler; Maxwell M Krem; Yajuan Liu; Shinae Namkoong; Govind Bhagat; Tomas Kirchhoff; Kenneth Offit; Henry Lynch; Peter H Wiernik; Mikhail Roshal; Mary Lou McMaster; Margaret Tucker; Jonathan R Fromm; Lynn R Goldin; Marshall S Horwitz
Journal:  Proc Natl Acad Sci U S A       Date:  2009-08-12       Impact factor: 11.205

10.  Tumor-suppressive function of protein-tyrosine phosphatase non-receptor type 23 in testicular germ cell tumors is lost upon overexpression of miR142-3p microRNA.

Authors:  Kiyoko Tanaka; Keiichi Kondo; Kenji Kitajima; Masatoshi Muraoka; Akinori Nozawa; Takahiko Hara
Journal:  J Biol Chem       Date:  2013-07-10       Impact factor: 5.157
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