| Literature DB >> 8600387 |
C Dib1, S Fauré, C Fizames, D Samson, N Drouot, A Vignal, P Millasseau, S Marc, J Hazan, E Seboun, M Lathrop, G Gyapay, J Morissette, J Weissenbach.
Abstract
The great increase in successful linkage studies in a number of higher eukaryotes during recent years has essentially resulted from major improvements in reference genetic linkage maps, which at present consist of short tandem repeat polymorphisms of simple sequences or microsatellites. We report here the last version of the Généthon human linkage map. This map consists of 5,264 short tandem (AC/TG)n repeat polymorphisms with a mean heterozygosity of 70%. The map spans a sex-averaged genetic distance of 3,699 cM and comprises 2,335 positions, of which 2,032 could be ordered with an odds ratio of at least 1,000:1 against alternative orders. The average interval size is 1.6 cM; 59% of the map is covered by intervals of 2 cM at most and 1% remains in intervals above 10 cM.Entities:
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Year: 1996 PMID： 8600387 DOI： 10.1038/380152a0
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962