Literature DB >> 950005

Ascorbic acid and cholesterol: effect of graded oral intakes on cholesterol conversion to bile acids in guinea-pigs.

D Hornig, H Weiser.   

Abstract

A significant correlation between liver ascorbic acid (AA) and total bile acids or liver bile acids has been established in guinea-pigs by direct determination of the bile acids, confirming an earlier hypothesis. The oxidation of cholesterol to bile acids is dependent on the AA status, but it cannot be further stimulated by AA when the animals are already on an adequate intake of the vitamin. This suggests that AA has a hypocholesterolaemic effect over a limited range of AA status.

Entities:  

Mesh:

Substances:

Year:  1976        PMID: 950005     DOI: 10.1007/bf01919833

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  20 in total

1.  Quantification of plasma cholesterol and triglyceride levels in hypercholesterolemic subjects receiving ascorbic acid supplements.

Authors:  V E Peterson; P A Crapo; J Weininger; H Ginsberg; J Olefsky
Journal:  Am J Clin Nutr       Date:  1975-06       Impact factor: 7.045

2.  Metabolic studies on scorbutic guinea pigs. 3. Catabolism of [4-C]cholesterol in vivo and in vitro.

Authors:  R Guchhait; B C Guha; N C Ganguli
Journal:  Biochem J       Date:  1963-02       Impact factor: 3.857

3.  Biliary lipids during vitamin C feeding in healthy persons.

Authors:  L Pedersen
Journal:  Scand J Gastroenterol       Date:  1975       Impact factor: 2.423

4.  [Plasma cholesterol level in healthy subjects and its modification by large doses of L(+)-ascorbic acid].

Authors:  A B Hanck
Journal:  Z Ernahrungswiss       Date:  1973-06

5.  Stimulation of (26- 14 C)cholesterol oxidation by ascorbic acid in scorbutic guinea-pigs.

Authors:  E Ginter; R Nemec; P Bobek
Journal:  Br J Nutr       Date:  1972-09       Impact factor: 3.718

6.  Lowered cholesterol catabolism in guinea pigs with chronic ascorbic acid deficiency.

Authors:  E Ginter; J Cerven; R Nemec; L Mikus
Journal:  Am J Clin Nutr       Date:  1971-10       Impact factor: 7.045

7.  The effect of ascorbic acid in vitro on the rat ovarian cholesterol side chain cleavage enzyme system.

Authors:  S Sulimovici; G S Boyd
Journal:  Steroids       Date:  1968-07       Impact factor: 2.668

8.  The effect of ascorbic acid on the lipid metabolism of guinea-pigs fed an atherogenic diet.

Authors:  E Ginter; P Bobek; J Babala; E Barbieriková
Journal:  Cor Vasa       Date:  1969

9.  The formation of cholic acid from 3alpha, 7alpha-dihydroxycoprostane in the rat.

Authors:  S BERGSTROM; S LINDSTEDT
Journal:  Biochim Biophys Acta       Date:  1956-03

10.  Atherosclerosis and vitamin C.

Authors:  C R Spittle
Journal:  Lancet       Date:  1971-12-11       Impact factor: 79.321

View more
  1 in total

1.  Reduction of gallstone formation by ascorbic acid in hamsters.

Authors:  E Ginter; L Mikus
Journal:  Experientia       Date:  1977-06-15
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.