| Literature DB >> 9492918 |
D De Clercq1, M Sacko, J Vercruysse, V vanden Bussche, A Landouré, A Diarra, B Gryseels, A Deelder.
Abstract
Eight weeks after mass chemotherapy with 40 mg/kg praziquantel in two villages in Office du Niger (an irrigation area in Mali, endemic for both Schistosoma haematobium and Schistosoma mansoni) the circulating anodic (CAA) and cathodic (CCA) antigen detection assays were carried out on serum and urine samples. Both prior and post treatment highest prevalence was measured with the urine-CCA assay. Cure rates determined by antigen detection were almost half that of the egg counting methods. It was shown that the reduction in intensity should be preferentially assessed by the serum-CAA assay. Compared with egg detection, a single antigen detection assay gave a much better assessment of the impact of chemotherapy.Entities:
Keywords: Africa; Africa South Of The Sahara; Antigens; Biology; Comparative Studies; Developing Countries; Diseases; Examinations And Diagnoses; French Speaking Africa; Immunity; Immunologic Factors; Laboratory Examinations And Diagnoses; Mali; Measurement; Parasitic Diseases--prevention and control; Physiology; Research Methodology; Research Report; Studies; Western Africa
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Year: 1997 PMID： 9492918 DOI： 10.1016/s0001-706x(97)00111-3
Source DB: PubMed Journal: Acta Trop ISSN： 0001-706X Impact factor: 3.112