| Literature DB >> 9484662 |
A Saitoh1, Y Suzuki, M Takeda, K Kubota, K Itoh, Y Tomino.
Abstract
Using a quantitative sandwich ELISA, we studied 17 patients with IgA nephropathy to determine if levels of urinary monocyte chemoattractant protein-1 (MCP-1) might reflect the disease activity. The levels of urinary MCP-1 in patients with the advanced stage were significantly higher than those in patients with the mild stage of the disease, or in healthy controls. The results showed a significant correlation between the levels of urinary MCP-1 and the disease activity, i.e., levels of urinary casts and urinary protein. It was thus suggested that the measurement of urinary MCP-1 is useful in evaluating the degree of renal injuries and/or prognosis in patients with IgA nephropathy.Entities:
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Year: 1998 PMID: 9484662 PMCID: PMC6808122 DOI: 10.1002/(sici)1098-2825(1998)12:1<1::aid-jcla1>3.0.co;2-f
Source DB: PubMed Journal: J Clin Lab Anal ISSN: 0887-8013 Impact factor: 2.352