| Literature DB >> 1819212 |
Y Tomino1, K Funabiki, H Ohmuro, M Shimizu, K Yokoyama, I Shirato, T Shirai, M Takahashi, H Koide.
Abstract
We studied, using ELISA, 27 patients with IgA nephropathy to determine if levels of urinary interleukin-6 (IL-6) might reflect the disease activity. The levels of urinary IL-6 in patients with the advanced stage were significantly higher than those in patients with the mild stage of the disease or in healthy adults. The results showed a significant correlation between the levels of urinary IL-6 and the disease activity, i.e., levels of urinary cast and urinary protein. It was thus suggested that the measurement of urinary IL-6 is useful in evaluating the degree of glomerular injuries and/or prognosis in patients with IgA nephropathy.Entities:
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Year: 1991 PMID： 1819212 DOI： 10.1159/000168359
Source DB: PubMed Journal: Am J Nephrol ISSN： 0250-8095 Impact factor: 3.754