Literature DB >> 9475215

The impact of nationally distributed guidelines on the management of paracetamol poisoning in accident and emergency departments. National Poison Information Service.

M C Bialas1, R J Evans, A D Hutchings, G Alldridge, P A Routledge.   

Abstract

OBJECTIVE: To assess the impact of the treatment guidelines on the management of paracetamol self poisoning in accident and emergency (A&E) departments.
METHODS: 24 A&E departments in Wales and England provided details of their management of paracetamol poisoning before and after the distribution of national treatment guidelines to all A&E departments in the United Kingdom.
RESULTS: Significant increases were seen in the availability of formal written policies, the display of treatment nomograms, the recommendation to treat beyond 16 hours after ingestion, and to use a lower line on the treatment nomogram for patients at special risk of paracetamol induced liver damage.
CONCLUSIONS: Regularly updated guidelines in the management of paracetamol poisoning should be displayed in A&E departments so that medical and nursing personnel have access to the best current information on the treatment of poisoning with this frequently used drug.

Entities:  

Mesh:

Substances:

Year:  1998        PMID: 9475215      PMCID: PMC1343000          DOI: 10.1136/emj.15.1.13

Source DB:  PubMed          Journal:  J Accid Emerg Med        ISSN: 1351-0622


  7 in total

1.  The effect of chronic alcohol intake on prognosis and outcome in paracetamol overdose.

Authors:  G P Bray; C Mowat; D F Muir; J M Tredger; R Williams
Journal:  Hum Exp Toxicol       Date:  1991-11       Impact factor: 2.903

2.  Improved outcome of paracetamol-induced fulminant hepatic failure by late administration of acetylcysteine.

Authors:  P M Harrison; R Keays; G P Bray; G J Alexander; R Williams
Journal:  Lancet       Date:  1990-06-30       Impact factor: 79.321

3.  Systemic glutathione deficiency in symptom-free HIV-seropositive individuals.

Authors:  R Buhl; H A Jaffe; K J Holroyd; F B Wells; A Mastrangeli; C Saltini; A M Cantin; R G Crystal
Journal:  Lancet       Date:  1989-12-02       Impact factor: 79.321

4.  Severe hepatotoxicity, acute renal failure, and pancytopenia in a young child after repeated acetaminophen overdosing.

Authors:  S M Douidar; I al-Khalil; R W Habersang
Journal:  Clin Pediatr (Phila)       Date:  1994-01       Impact factor: 1.168

5.  Hepatotoxicity due to repeated intake of low doses of paracetamol.

Authors:  L S Eriksson; U Broomé; M Kalin; M Lindholm
Journal:  J Intern Med       Date:  1992-05       Impact factor: 8.989

6.  Paracetamol toxicity: is enzyme induction important?

Authors:  J A Smith; I D Hine; P Beck; P A Routledge
Journal:  Hum Toxicol       Date:  1986-12

7.  Safety of late acetylcysteine treatment in paracetamol poisoning.

Authors:  D Parker; J P White; D Paton; P A Routledge
Journal:  Hum Exp Toxicol       Date:  1990-01       Impact factor: 2.903

  7 in total
  4 in total

1.  TOXBASE: poisons information on the internet.

Authors:  D N Bateman; A M Good; W J Laing; C A Kelly
Journal:  Emerg Med J       Date:  2002-01       Impact factor: 2.740

2.  Identifying adults at risk of paracetamol toxicity in the acute dental setting: development of a clinical algorithm.

Authors:  N V Nayyer; J Byers; C Marney
Journal:  Br Dent J       Date:  2014-03       Impact factor: 1.626

3.  Paracetamol (acetaminophen) poisoning. No need to change current guidelines to accident departments.

Authors:  P Routledge; J A Vale; D N Bateman; G D Johnston; A Jones; A Judd; S Thomas; G Volans; L F Prescott; A Proudfoot
Journal:  BMJ       Date:  1998-12-12

4.  Medical management of deliberate drug overdose: a neglected area for suicide prevention?

Authors:  D Gunnell; D Ho; V Murray
Journal:  Emerg Med J       Date:  2004-01       Impact factor: 2.740

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.