Literature DB >> 14734371

Medical management of deliberate drug overdose: a neglected area for suicide prevention?

D Gunnell1, D Ho, V Murray.   

Abstract

OBJECTIVES: Overdoses account for a quarter of all suicides in England. The number of people who survive the immediate effects of their overdose long enough to reach medical attention, but who subsequently die in hospital is unknown. The aim of this study was to determine the proportion of overdose suicides dying in hospital and describe their sociodemographic characteristics.
METHOD: Cross sectional analysis of routinely collected Hospital Episode Statistics data for England (1997 to 1999) to identify hospital admissions for overdose among people aged 12+ and the outcome of these admissions.
RESULTS: Between 1997 and 1999 there were 233 756 hospital admissions for overdose, 1149 (0.5%) of these ended in the death of the patient such deaths accounted for 28% [corrected] of all overdose suicides and 8% [corrected] of total suicides. The median time between admission and death was three days (interquartile range one to nine days). The most commonly identified drugs taken in fatal overdose were paracetamol compounds, benzodiazepines, and tricyclic/tetracyclic antidepressants.
CONCLUSION: Around a quarter of all overdose suicide deaths occur subsequent to hospital admission. Further more detailed research is required to discover if better pre-admission and in-hospital medical management of those taking serious overdoses may prevent some of these deaths.

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Year:  2004        PMID: 14734371      PMCID: PMC1756353          DOI: 10.1136/emj.2003.000935

Source DB:  PubMed          Journal:  Emerg Med J        ISSN: 1472-0205            Impact factor:   2.740


  16 in total

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Authors:  M Eddleston
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Authors:  Michael Eddleston; Michael R Phillips
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2.  From pesticides to medicinal drugs: time series analyses of methods of self-harm in Sri Lanka.

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Authors:  U Hegerl
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6.  Psychological autopsy study of suicide in three rural and semi-rural districts of Sri Lanka.

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Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2008-02-05       Impact factor: 4.328

7.  Age-sex differences in medicinal self-poisonings: a population-based study of deliberate intent and medical severity.

Authors:  Anne E Rhodes; Jennifer Bethell; Julie Spence; Paul S Links; David L Streiner; R Liisa Jaakkimainen
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2008-05-29       Impact factor: 4.328

Review 8.  Is there evidence for negative effects of antidepressants on suicidality in depressive patients? A systematic review.

Authors:  Hans-Jürgen Möller
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Authors:  David Gunnell; Michael Eddleston
Journal:  Int J Epidemiol       Date:  2003-12       Impact factor: 7.196

10.  The hazards of gastric lavage for intentional self-poisoning in a resource poor location.

Authors:  Michael Eddleston; Sapumal Haggalla; K Reginald; K Sudarshan; M Senthilkumaran; Lakshman Karalliedde; Ariaranee Ariaratnam; M H Rezvi Sheriff; David A Warrell; Nick A Buckley
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