Literature DB >> 9468556

Immunohistochemical demonstration of alpha-fetoprotein in small hepatocellular carcinoma.

K Sato1, M Tanaka, T Kusaba, H Fukuda, K Tanikawa.   

Abstract

We demonstrated immunohistochemical staining of a-fetoprotein (AFP) in small hepatocellular carcinoma (HCC). Fifty-six patients with HCC less than 2 cm in diameter were studied. Twenty-five HCCs (44.6%) were positive for AFP-staining. The positive rate of AFP-staining in HCC tissue was higher in the patients with serum AFP concentration above 20 ng/ml than that of the patients with below 20 ng/ml. AFP-staining was demonstrated on the rough endoplasmic reticulum of HCC cells by immuno-electron microscopy. AFP-staining of tissue specimens obtained by fine needle biopsy is useful in the histologic diagnosis of HCC.

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Year:  1998        PMID： 9468556

Source DB:  PubMed          Journal:  Oncol Rep        ISSN： 1021-335X            Impact factor:   3.906


  7 in total

1.  Surveillance and diagnosis of hepatocellular carcinoma in patients with cirrhosis.

Authors:  Lorenzo Andreana; Graziella Isgrò; Maria Pleguezuelo; Giacomo Germani; Andrew K Burroughs
Journal:  World J Hepatol       Date:  2009-10-31

2.  The comparative study on ultrastructure and immunohistochemistry in AFP negative and positive hepatocellular carcinoma.

Authors:  Meirong Zheng; Youbing Ruan; Mulan Yang; Yang Guan; Zhongbi Wu
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2004

3.  Alpha-fetoprotein specific CD4 and CD8 T cell responses in patients with hepatocellular carcinoma.

Authors:  Shahriar Behboudi; Stephen P Pereira
Journal:  World J Hepatol       Date:  2010-07-27

4.  L-Theanine-Treated Adipose-Derived Mesenchymal Stem Cells Alleviate the Cytotoxicity Induced by N-Nitrosodiethylamine in Liver.

Authors:  Yun-Ju Lai; Yi-Ting Sung; Yi-An Lai; Li-Nian Chen; Tung-Sheng Chen; Chiang-Ting Chien
Journal:  Tissue Eng Regen Med       Date:  2022-08-27       Impact factor: 4.451

5.  A novel diagnostic marker, p28GANK distinguishes hepatocellular carcinoma from potential mimics.

Authors:  Xiaoyong Fu; Lu Tan; Shuqin Liu; Honghai Li; Lei Chen; Jianmin Qin; Mengchao Wu; Hongyang Wang
Journal:  J Cancer Res Clin Oncol       Date:  2004-06-19       Impact factor: 4.553

6.  Fine needle aspiration biopsy of the liver: Algorithmic approach and current issues in the diagnosis of hepatocellular carcinoma.

Authors:  Aileen Wee
Journal:  Cytojournal       Date:  2005-06-08       Impact factor: 2.091

7.  Expansion of anti-mesothelin specific CD4+ and CD8+ T cell responses in patients with pancreatic carcinoma.

Authors:  Yuan Chen; Lakshmana Ayaru; Sanju Mathew; Emma Morris; Stephen P Pereira; Shahriar Behboudi
Journal:  PLoS One       Date:  2014-02-10       Impact factor: 3.240
  7 in total

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