| Literature DB >> 946084 |
Abstract
The in-home use of paint removers containing methylene chloride results in the absorption of this solvent, which is metabolized to carbon monoxide. Exposure for two to three hours can result in the elevation of carboxyhemoglobin (COHb) to levels that stress the cardiovascular system. The metabolic formation of COHb continues following the paint-remover exposure, doubling the duration of the cardiovascular stress produced by a comparable COHb level after exposure to CO. Patients with diseased cardiovascular systems may not be able to tolerate this unexpected stress.Entities:
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Year: 1976 PMID: 946084
Source DB: PubMed Journal: JAMA ISSN: 0098-7484 Impact factor: 56.272