Literature DB >> 9441055

Tuberculosis elimination--what's to stop us?

L B Reichman1.   

Abstract

It is well recognized and has oft been stated that tuberculosis (TB) is the largest cause of death from a single infection worldwide; it infects fully one-third of the world's population, is fully 100% curable and 100% preventable and yet is nowhere near being eliminated in any area of the globe, including the most developed nations. The failure to eliminate this, possibly the most easily eliminatable of all scourges, must rank as one of mankind's most serious ongoing blunders. After all, we know the pathogenesis, we know the transmission, we know how to diagnose, treat and prevent almost all cases, yet TB killed more individuals in 1996 than it did when Robert Koch discovered the bacillus that causes TB more than a century ago. TB is different from almost any other disease in that cases of TB must be actively sought and treated to keep them from spreading to others. In most diseases the untreated case dies and harms nobody. In TB the untreated or improperly treated case becomes resistant and spreads drug-resistant TB until it is found and properly treated. We physicians love to blame our patients for noncompliance in taking drugs. However, our failure to deal with TB clearly and documentedly rests with a lack of compliance on several levels. TB will nerve be eliminated until this lack of compliance on all levels is addressed and corrected.

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Year:  1997        PMID: 9441055

Source DB:  PubMed          Journal:  Int J Tuberc Lung Dis        ISSN: 1027-3719            Impact factor:   2.373


  12 in total

1.  Immune mechanism: a 'double-edged sword'.

Authors:  Mustaffa Musa
Journal:  Malays J Med Sci       Date:  2013-05

2.  Fluorescence In situ hybridization assay using peptide nucleic acid probes for differentiation between tuberculous and nontuberculous mycobacterium species in smears of mycobacterium cultures.

Authors:  H Stender; K Lund; K H Petersen; O F Rasmussen; P Hongmanee; H Miörner; S E Godtfredsen
Journal:  J Clin Microbiol       Date:  1999-09       Impact factor: 5.948

3.  Is the eradication of tuberculosis 'yesterday's ambition' or 'tomorrow's triumph'?

Authors:  Alimuddin Zumla; John M Grange
Journal:  Clin Med (Lond)       Date:  2010-10       Impact factor: 2.659

4.  The tuberculosis epidemic. Scientific challenges and opportunities.

Authors:  A M Ginsberg
Journal:  Public Health Rep       Date:  1998 Mar-Apr       Impact factor: 2.792

5.  Unusual forms of spinal tuberculosis.

Authors:  Jaco du Plessis; Savvas Andronikou; Salomine Theron; Nicky Wieselthaler; Murray Hayes
Journal:  Childs Nerv Syst       Date:  2007-11-07       Impact factor: 1.475

Review 6.  To control and beyond: moving towards eliminating the global tuberculosis threat.

Authors:  Timothy F Brewer; S Jody Heymann
Journal:  J Epidemiol Community Health       Date:  2004-10       Impact factor: 3.710

Review 7.  Fixed-dose combination drugs for tuberculosis: application in standardised treatment regimens.

Authors:  Bjørn Blomberg; Bernard Fourie
Journal:  Drugs       Date:  2003       Impact factor: 9.546

8.  Tuberculosis chemotherapy in the 21 century: Back to the basics.

Authors:  Jyotsna M Joshi
Journal:  Lung India       Date:  2011-07

9.  A Global Public Goods Approach to the Health of Migrants.

Authors:  Heather Widdows; Herjeet Marway
Journal:  Public Health Ethics       Date:  2015-07       Impact factor: 1.940

10.  Video-assisted thoracic surgery for tubercular spondylitis.

Authors:  Roop Singh; Paritosh Gogna; Sanjeev Parshad; Rajender Kumar Karwasra; Parmod Kumar Karwasra; Kiranpreet Kaur
Journal:  Minim Invasive Surg       Date:  2014-04-03
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