Literature DB >> 23966827

Immune mechanism: a 'double-edged sword'.

Mustaffa Musa1.   

Abstract

Immunology has now developed into an independent discipline in medicine which covers not only germ infection which is related to immunity solely but also covers a lot of non-infectious diseases such as autoimmune disease, allergies, and others. Therefore, "The Immune Mechanism: "A Double-Edged Sword" means that the immune mechanism (consisted of antibody mediated mechanism and T cell mediated mechanism), just like one edge playing the role of giving benefit (immunity) as it destroys the agent of infection, and another one can be detrimental as it will cause tissue/cell damages and then give rise to immune diseases (immunopathology). Now, the prevalence of these immune diseases is on the rise and has become a new challenge to our country towards developed country in 2020. Therefore, we have to make ample preparation (laboratory facilities/services, main power, and research) from now on in order to face the problems and challenges.

Entities:  

Keywords:  SLE; immune response; tuberculosis; vaccine

Year:  2013        PMID: 23966827      PMCID: PMC3743984     

Source DB:  PubMed          Journal:  Malays J Med Sci        ISSN: 1394-195X


  21 in total

Review 1.  Host responses and antigens involved in protective immunity to Mycobacterium tuberculosis.

Authors:  P Andersen
Journal:  Scand J Immunol       Date:  1997-02       Impact factor: 3.487

2.  Drug resistance among tubercle bacilli from pulmonary tuberculosis cases in central India.

Authors:  N Hemvani; D S Chitnis; G C Bhatia; N Sharma
Journal:  Indian J Med Sci       Date:  2001-07

Review 3.  Immunity to intracellular microbial pathogens.

Authors:  S H Kaufmann
Journal:  Immunol Today       Date:  1995-07

Review 4.  Variation in protection by BCG: implications of and for heterologous immunity.

Authors:  P E Fine
Journal:  Lancet       Date:  1995-11-18       Impact factor: 79.321

5.  Ethnic distribution of patients with S.L.E. seen in university hospital, Kuala Lumpur 1967--1976.

Authors:  A O Frank
Journal:  Med J Malaysia       Date:  1980-03

6.  Antimicrobial activity of MHC class I-restricted CD8+ T cells in human tuberculosis.

Authors:  S Cho; V Mehra; S Thoma-Uszynski; S Stenger; N Serbina; R J Mazzaccaro; J L Flynn; P F Barnes; S Southwood; E Celis; B R Bloom; R L Modlin; A Sette
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-24       Impact factor: 11.205

7.  Incidence of systemic lupus erythematosus. Race and gender differences.

Authors:  D J McCarty; S Manzi; T A Medsger; R Ramsey-Goldman; R E LaPorte; C K Kwoh
Journal:  Arthritis Rheum       Date:  1995-09

Review 8.  New vaccines against tuberculosis.

Authors:  T Mark Doherty
Journal:  Trop Med Int Health       Date:  2004-07       Impact factor: 2.622

9.  The autoantibody profile and its association with clinical manifestations in Malay SLE patients.

Authors:  C H Che Maraina; M D Kamaliah; M Ishak
Journal:  Asian Pac J Allergy Immunol       Date:  2004-03       Impact factor: 2.310

10.  Mycobacterium tuberculosis invades and replicates within type II alveolar cells.

Authors:  L E Bermudez; J Goodman
Journal:  Infect Immun       Date:  1996-04       Impact factor: 3.441

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  2 in total

Review 1.  Epigenetics in immune-mediated pulmonary diseases.

Authors:  Yu Liu; Hui Li; Tao Xiao; Qianjin Lu
Journal:  Clin Rev Allergy Immunol       Date:  2013-12       Impact factor: 8.667

Review 2.  Cross-Talk between Cancer Cells and the Tumour Microenvironment: The Role of the 5-Lipoxygenase Pathway.

Authors:  Gillian Y Moore; Graham P Pidgeon
Journal:  Int J Mol Sci       Date:  2017-01-24       Impact factor: 5.923

  2 in total

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