Literature DB >> 9438015

Bis-quinolinium cyclophanes: 6,10-diaza-3(1,3),8(1,4)-dibenzena-1,5(1,4)- diquinolinacyclodecaphane (UCL 1684), the first nanomolar, non-peptidic blocker of the apamin-sensitive Ca(2+)-activated K+ channel.

J C Rosa1, D Galanakis, C R Ganellin, P M Dunn, D H Jenkinson.   

Abstract

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Year:  1998        PMID： 9438015     DOI： 10.1021/jm970571a

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  33 in total

1.  Pharmacological characterization of small-conductance Ca(2+)-activated K(+) channels stably expressed in HEK 293 cells.

Authors:  D Strøbaek; T D Jørgensen; P Christophersen; P K Ahring; S P Olesen
Journal:  Br J Pharmacol       Date:  2000-03       Impact factor: 8.739

2.  Effects of inhibitors of small- and intermediate-conductance calcium-activated potassium channels, inwardly-rectifying potassium channels and Na(+)/K(+) ATPase on EDHF relaxations in the rat hepatic artery.

Authors:  D A Andersson; P M Zygmunt; P Movahed; T L Andersson; E D Högestätt
Journal:  Br J Pharmacol       Date:  2000-04       Impact factor: 8.739

3.  Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses.

Authors:  David A Jacobson; Felipe Mendez; Michael Thompson; Jacqueline Torres; Olivia Cochet; Louis H Philipson
Journal:  J Physiol       Date:  2010-07-19       Impact factor: 5.182

Review 4.  Endothelial Ca+-activated K+ channels in normal and impaired EDHF-dilator responses--relevance to cardiovascular pathologies and drug discovery.

Authors:  Ivica Grgic; Brajesh P Kaistha; Joachim Hoyer; Ralf Köhler
Journal:  Br J Pharmacol       Date:  2009-03-19       Impact factor: 8.739

5.  Endothelin-1 shifts the mediator of bradykinin-induced relaxation from NO to H2 O2 in resistance arteries from patients with cardiovascular disease.

Authors:  Thomas M Leurgans; Maria Bloksgaard; Jonathan R Brewer; Luis A Bagatolli; Maise H Fredgart; Kristoffer Rosenstand; Maria L Hansen; Lars M Rasmussen; Akhmadjon Irmukhamedov; Jo Gr De Mey
Journal:  Br J Pharmacol       Date:  2016-04-06       Impact factor: 8.739

Review 6.  K+ channel modulators for the treatment of neurological disorders and autoimmune diseases.

Authors:  Heike Wulff; Boris S Zhorov
Journal:  Chem Rev       Date:  2008-05       Impact factor: 60.622

7.  New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1.

Authors:  Nichole Coleman; Brandon M Brown; Aida Oliván-Viguera; Vikrant Singh; Marilyn M Olmstead; Marta Sofia Valero; Ralf Köhler; Heike Wulff
Journal:  Mol Pharmacol       Date:  2014-06-23       Impact factor: 4.436

8.  Compounds that block both intermediate-conductance (IK(Ca)) and small-conductance (SK(Ca)) calcium-activated potassium channels.

Authors:  M Malik-Hall; C R Ganellin; D Galanakis; D H Jenkinson
Journal:  Br J Pharmacol       Date:  2000-04       Impact factor: 8.739

9.  Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure.

Authors:  Ananthakrishnan Sankaranarayanan; Girija Raman; Christoph Busch; Tim Schultz; Pavel I Zimin; Joachim Hoyer; Ralf Köhler; Heike Wulff
Journal:  Mol Pharmacol       Date:  2008-10-27       Impact factor: 4.436

10.  Endothelium-dependent hyperpolarization-related relaxations diminish with age in murine saphenous arteries of both sexes.

Authors:  Ramesh Chennupati; Wouter H Lamers; S Eleonore Koehler; Jo G R De Mey
Journal:  Br J Pharmacol       Date:  2013-08       Impact factor: 8.739
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