| Literature DB >> 943105 |
L D Koller, J H Exon, J G Roan.
Abstract
A single dose of lead administered orally or intraperitoneally (IP) to mice stimulated formation of IgM antibody. Cadmium caused an increase in IgM antibody formation when injected ip but resulted in a slight decrease when given orally. Lead, orally or ip, significantly reduced IgG antibody but the IgG antibody response decreased only when cadmium was given orally and increased when injected ip. Since responses vary according to route of administration, experiments should be designed so that experimental exposure will simulate natural exposure in order to develop comparable data.Entities:
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Year: 1976 PMID： 943105 DOI： 10.3181/00379727-151-39205
Source DB: PubMed Journal: Proc Soc Exp Biol Med ISSN： 0037-9727