Literature DB >> 9430089

Cholesterol lowering effects of rhubarb stalk fiber in hypercholesterolemic men.

V Goel1, B Ooraikul, T K Basu.   

Abstract

OBJECTIVE: The present study was undertaken to examine the lipid lowering effects of rhubarb fiber prepared by blanching and drying fresh rhubarb stalks. The new fiber source contained 74% dietary fiber, on dry weight basis, with 66% insoluble and 8% soluble fiber.
DESIGN: Ten hypercholesterolemic men were assigned to consume 27 g of ground rhubarb stalk fiber per day for 4 weeks. The dietary intake in terms of total energy, lipid and cholesterol was kept unaltered during the study period. Changes in serum lipid profile were monitored by obtaining blood samples before and after the fiber intervention.
RESULTS: Rhubarb fiber supplementation resulted in significant lowering of serum total cholesterol (8%) and low-density lipoprotein (LDL) cholesterol (9%), while high-density lipoprotein cholesterol (HDL) concentrations remained unchanged. The depressed total and LDL cholesterol levels returned to baseline after the fiber supplementation was withdrawn for 1 month.
CONCLUSION: The rhubarb stalk fiber is effective in lowering serum cholesterol concentrations, especially LDL cholesterol, in hypercholesterolemic men. These results signify the potential use of underutilized rhubarb crop.

Entities:  

Mesh:

Substances:

Year:  1997        PMID: 9430089

Source DB:  PubMed          Journal:  J Am Coll Nutr        ISSN: 0731-5724            Impact factor:   3.169


  7 in total

1.  The Effect of Isolated and Synthetic Dietary Fibers on Markers of Metabolic Diseases in Human Intervention Studies: A Systematic Review.

Authors:  Anissa M Armet; Edward C Deehan; Julia V Thöne; Sarah J Hewko; Jens Walter
Journal:  Adv Nutr       Date:  2020-03-01       Impact factor: 8.701

Review 2.  A Review on Rhubarb-Derived Substances as Modulators of Cardiovascular Risk Factors-A Special Emphasis on Anti-Obesity Action.

Authors:  Oleksandra Liudvytska; Joanna Kolodziejczyk-Czepas
Journal:  Nutrients       Date:  2022-05-13       Impact factor: 6.706

3.  Lyophilized carrot ingestion lowers lipemia and beneficially affects cholesterol metabolism in cholesterol-fed C57BL/6J mice.

Authors:  Catherine Nicolle; Elyett Gueux; Claudine Lab; Lydia Jaffrelo; Edmond Rock; Andrzej Mazur; Pierre Amouroux; Christian Rémésy
Journal:  Eur J Nutr       Date:  2004-01-28       Impact factor: 5.614

4.  Renoprotective effect of hydroalcoholic extract of Rheum ribes root in diabetic female rats.

Authors:  Shokri Hamzeh; Farah Farokhi; Reza Heydari; Ramin Manaffar
Journal:  Avicenna J Phytomed       Date:  2014-11

5.  Rheum turkestanicum rhizomes possess anti-hypertriglyceridemic, but not hypoglycemic or hepatoprotective effect in experimental diabetes.

Authors:  Mousa-Al-Reza Hadjzadeh; Ziba Rajaei; Esmaeil Khodaei; Maryam Malek; Habib Ghanbari
Journal:  Avicenna J Phytomed       Date:  2017 Jan-Feb

6.  Study of the effect of the essential oil (extract) of rhubarb stem (shoot) on glycosylated hemoglobin and fasting blood glucose levels in patients with type II diabetes.

Authors:  Fahimeh Shojaei Shad; Maryam Jahantigh Haghighi
Journal:  Biomedicine (Taipei)       Date:  2018-11-26

7.  Hypolipidemic effects of three purgative decoctions.

Authors:  Sung-Hui Tseng; Ting-Yi Chien; Jiun-Rong Chen; I-Hsin Lin; Ching-Chiung Wang
Journal:  Evid Based Complement Alternat Med       Date:  2011-02-14       Impact factor: 2.629

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.