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Literature DB >> 942927

Morphine suppression of ethanol withdrawal in mice.

K Blum, J E Wallace, H A Schwerter, J D Eubanks.

Abstract

The acute administration of morphine, alcohol or dopamine results in a pronounced suppression of the convulsions produced by alcohol in mice. The suppressive action of morphine on alcohol withdrawal in the mouse apparently is not a product of morphine intoxication, but rather to some other specific interaction between alcohol and morphine in the central nervous system. The conclusion suggest that dopamine may play a significant role as a modulator in convulsions produced during alcohol withdrawal.

Entities: Chemical Disease Species

Mesh：

Substances：
Ethanol
Morphine
Dopamine

Year: 1976 PMID： 942927 DOI： 10.1007/bf01932634

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

18 in total

1. Tetrahydroisoquinolines in vivo. I. Rat brain formation of salsolinol, a condensation product of dopamine and acetaldehyde, under certain conditions during ethanol intoxication.

Authors: M A Collins; M G Bigdeli
Journal: Life Sci Date: 1975-02-15 Impact factor: 5.037

2. Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse.

Authors: T J HALEY; W G MCCORMICK
Journal: Br J Pharmacol Chemother Date: 1957-03

3. Sensitisation to morphine by experimentally induced alcoholism in white mice.

Authors: I VENHO; R EEROLA; E V VENHO; O VARTIAINEN
Journal: Ann Med Exp Biol Fenn Date: 1955

4. Morphine induced calcium depletion in discrete regions of rat brain.

Authors: H L Cardenas; D H Ross
Journal: J Neurochem Date: 1975-03 Impact factor: 5.372

5. Morphine-induced suppression of voluntary alcohol drinking in rats.

Authors: J D Sinclair; J Adkins; S Walker
Journal: Nature Date: 1973-12-14 Impact factor: 49.962

6. The dopamine-releasing actions of neuroleptics and ethanol.

Authors: P Seeman; T Lee
Journal: J Pharmacol Exp Ther Date: 1974-07 Impact factor: 4.030

7. Development of morphine dependence in rats: lack of effect of previous ingestion of other drugs.

Authors: I P Stolerman; R Kumar; H Steinberg
Journal: Psychopharmacologia Date: 1971

8. On the effects of some heterocyclic compounds on the enzymic activity of liver alcohol dehydrogenase.

Authors: H Theorell; T Yonetani; B Sjöberg
Journal: Acta Chem Scand Date: 1969

9. Alcohol dependence and opiate dependence: lack of relationship in mice.

Authors: A Goldstein; B A Judson
Journal: Science Date: 1971-04-16 Impact factor: 47.728

10. Morphine and ethanol: selective depletion of regional brain calcium.

Authors: D H Ross; M A Medina; H L Cardenas
Journal: Science Date: 1974-10-04 Impact factor: 47.728

13 in total

1. Fifty Years in the Development of a Glutaminergic-Dopaminergic Optimization Complex (KB220) to Balance Brain Reward Circuitry in Reward Deficiency Syndrome: A Pictorial.

Authors: K Blum; M Febo; R D Badgaiyan
Journal: Austin Addict Sci Date: 2016-10-12

2. Can the chronic administration of the combination of buprenorphine and naloxone block dopaminergic activity causing anti-reward and relapse potential?

Authors: Kenneth Blum; Thomas J H Chen; John Bailey; Abdalla Bowirrat; John Femino; Amanda L C Chen; Thomas Simpatico; Siobhan Morse; John Giordano; Uma Damle; Mallory Kerner; Eric R Braverman; Frank Fornari; B William Downs; Cynthia Rector; Debmayla Barh; Marlene Oscar-Berman
Journal: Mol Neurobiol Date: 2011-09-24 Impact factor: 5.590

3. Morphine preference of alcohol-avoiding and alcohol-preferring C57BL mice.

Authors: G Whitney; G P Horowitz
Journal: Behav Genet Date: 1978-03 Impact factor: 2.805

4. Effects of ethanol on turnover and function of striatal dopamine.

Authors: H Lai; W L Makous; A Horita; H Leung
Journal: Psychopharmacology (Berl) Date: 1979-03-14 Impact factor: 4.530

5. Narcotic antagonism of seizures induced by a dopamine-derived tetrahydroisoquinoline alkaloid.

Authors: K Blum
Journal: Experientia Date: 1988-09-15

6. Neurogenetics and Nutrigenomics of Neuro-Nutrient Therapy for Reward Deficiency Syndrome (RDS): Clinical Ramifications as a Function of Molecular Neurobiological Mechanisms.

Authors: Kenneth Blum; Marlene Oscar-Berman; Elizabeth Stuller; David Miller; John Giordano; Siobhan Morse; Lee McCormick; William B Downs; Roger L Waite; Debmalya Barh; Dennis Neal; Eric R Braverman; Raquel Lohmann; Joan Borsten; Mary Hauser; David Han; Yijun Liu; Manya Helman; Thomas Simpatico
Journal: J Addict Res Ther Date: 2012-11-27

7. The effects of ethanol, phenobarbital, and baclofen on ethanol withdrawal in the rhesus monkey.

Authors: J S Tarika; G Winger
Journal: Psychopharmacology (Berl) Date: 1980 Impact factor: 4.530

8. Withdrawal from Buprenorphine/Naloxone and Maintenance with a Natural Dopaminergic Agonist: A Cautionary Note.

Authors: Kenneth Blum; Marlene Oscar-Berman; John Femino; Roger L Waite; Lisa Benya; John Giordano; Joan Borsten; William B Downs; Eric R Braverman; Raquel Loehmann; Kristina Dushaj; David Han; Thomas Simpatico; Mary Hauser; Debmalya Barh; Thomas McLaughlin
Journal: J Addict Res Ther Date: 2013-04-23

9. Pro-Dopamine Regulator - (KB220) to Balance Brain Reward Circuitry in Reward Deficiency Syndrome (RDS).

Authors: Kenneth Blum; Marcelo Febo; Lyle Fried; David Baron; Eric R Braverman; Kristina Dushaj; Mona Li; Zsolt Demetrovics; Rajendra D Badgaiyan
Journal: J Reward Defic Syndr Addict Sci Date: 2017-04-28

Review 10. Morphine for Intravenous Patient-Controlled Analgesia May Inhibit Delirium Tremens: A Case Report and Literature Review.

Authors: Chia-Ta Chan; Wen-Wei Liao; William Huang
Journal: Medicine (Baltimore) Date: 2015-10 Impact factor: 1.817