Literature DB >> 9425275

Immunochemical evidence for increased formation of advanced glycation end products and inhibition by aminoguanidine in diabetic rat lenses.

K Matsumoto1, K Ikeda, S Horiuchi, H Zhao, E C Abraham.   

Abstract

Water-soluble and urea-soluble protein fractions from control and streptozotocin-diabetic rats were analyzed for AGEs with a CML-specific monoclonal anti-AGE antibody and a polyclonal anti-AGE antibody. AGEs, CML in particular, were significantly increased in the diabetic rats whereas aminoguandine treatment resulted in significant decrease in AGEs. The data also confirm that CML, a glycoxidation product, is a major epitope of AGE structures in lenses.

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Year:  1997        PMID： 9425275     DOI： 10.1006/bbrc.1997.7744

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  9 in total

Review 1.  Advanced glycation: an important pathological event in diabetic and age related ocular disease.

Authors:  A W Stitt
Journal:  Br J Ophthalmol       Date:  2001-06       Impact factor: 4.638

2.  Glycoxidized particles mimic lipofuscin accumulation in aging eyes: a new age-related macular degeneration model in rabbits.

Authors:  Tsutomu Yasukawa; Peter Wiedemann; Stefan Hoffmann; Johannes Kacza; Wolfram Eichler; Yu-Sheng Wang; Akiko Nishiwaki; Johannes Seeger; Yuichiro Ogura
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2007-04-04       Impact factor: 3.117

3.  Advanced glycation end products in human senile and diabetic cataractous lenses.

Authors:  S Zarina; H R Zhao; E C Abraham
Journal:  Mol Cell Biochem       Date:  2000-07       Impact factor: 3.396

4.  Cleavage of in vitro and in vivo formed lens protein cross-links by a novel cross-link breaker.

Authors:  Seth Hollenbach; Prajitha Thampi; Tito Viswanathan; Edathara C Abraham
Journal:  Mol Cell Biochem       Date:  2003-01       Impact factor: 3.396

Review 5.  Too sweet: Problems of protein glycation in the eye.

Authors:  Eloy Bejarano; Allen Taylor
Journal:  Exp Eye Res       Date:  2018-08-24       Impact factor: 3.467

6.  Role of the specifically targeted lysine residues in the glycation dependent loss of chaperone activity of alpha A- and alpha B-crystallins.

Authors:  Edathara C Abraham; Jin Huaqian; Atya Aziz; Anbarasu Kumarasamy; Poppy Datta
Journal:  Mol Cell Biochem       Date:  2007-12-25       Impact factor: 3.396

7.  Advanced glycation endproducts in human diabetic and non-diabetic cataractous lenses.

Authors:  Rajko Pokupec; Miro Kalauz; Niksa Turk; Zdenka Turk
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2003-04-16       Impact factor: 3.117

8.  Fundus autofluorescence and fate of glycoxidized particles injected into subretinal space in rabbit age-related macular degeneration model.

Authors:  Megumi Hirata; Tsutomu Yasukawa; Peter Wiedemann; Erika Kimura; Noriyuki Kunou; Wolfram Eichler; Ayae Takase; Rina Sato; Yuichiro Ogura
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2009-03-28       Impact factor: 3.117

9.  Immunochemical detection of glycated lens crystallins and their circulating autoantibodies in human serum during aging.

Authors:  Mala Ranjan; Sujatha Nayak; Tanuja Kosuri; Beedu Sashidhar Rao
Journal:  Mol Vis       Date:  2008-11-17       Impact factor: 2.367
  9 in total

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