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Literature DB >> 941902

Assignment of the structural gene for human beta glucuronidase to chromosome 7 and tetrameric association of subunits in the enzyme molecule.

Abstract

The structural locus for human beta glucuronidase is assigned to chromosome 7, a localization based upon concordant segregation of the expression of the human enzyme and the presence of human chromosome 7 in somatic cell hybrid clones derived independently from fusions of different human and mouse cells. Hybrid clones containing only human chromosome 7 are included in this study. Electrophoresis of beta glucuronidase also has revealed that human beta glucuronidase has a tetrametric structure.

Entities: Gene Species

Mesh：

Substances：
Glucuronidase

Year: 1976 PMID： 941902 PMCID： PMC1685053

Source DB: PubMed Journal: Am J Hum Genet ISSN： 0002-9297 Impact factor: 11.025

22 in total

1. PURIFICATION AND PROPERTIES OF HUMAN LIVER BETA-GLUCURONIDASE.

Authors: B U MUSA; R P DOE; U S SEAL
Journal: J Biol Chem Date: 1965-07 Impact factor: 5.157

2. Confirmation of the synteny of the human genes for mannose phosphate isomerase and pyruvate kinase and of their assignment to chromosome 15.

Authors: C J Chern; C M Croce
Journal: Cytogenet Cell Genet Date: 1975

3. The effect of mutation on the intracellular location of beta-glucuronidase.

Authors: K PAIGEN
Journal: Exp Cell Res Date: 1961-11 Impact factor: 3.905

4. Preferential retention of the human chromosome C-7 in human-(thymidine kinase deficient) mouse hybrid cells.

Authors: C M Croce; B B Knowles; H Koprowski
Journal: Exp Cell Res Date: 1973-12 Impact factor: 3.905

5. A rapid banding technique for human chromosomes.

Authors: M Seabright
Journal: Lancet Date: 1971-10-30 Impact factor: 79.321

6. Uptake of beta-glucuronidase by deficient human fibroblasts.

Authors: D Lagunoff; D M Nicol; P Pritzi
Journal: Lab Invest Date: 1973-10 Impact factor: 5.662

7. Beta glucuronidase deficiency: report of clinical, radiologic, and biochemical features of a new mucopolysaccharidosis.

Authors: W S Sly; B A Quinton; W H McAlister; D L Rimoin
Journal: J Pediatr Date: 1973-02 Impact factor: 4.406

8. Loss of T-antigen from somatic hybrids between mouse cells and SV40-transformed human cells.

Authors: M C Weiss; B Ephrussi; L J Scaletta
Journal: Proc Natl Acad Sci U S A Date: 1968-04 Impact factor: 11.205

9. Assignment of the T-antigen gene of simian virus 40 to human chromosome C-7.

Authors: C M Croce; A J Girardi; H Koprowski
Journal: Proc Natl Acad Sci U S A Date: 1973-12 Impact factor: 11.205

10. Somatic cell hybrids between mouse peritoneal macrophages and SV40-transformed human cells. I. Positive control of the transformed phenotype by the human chromosome 7 carrying the SV40 genome.

Authors: C M Croce; H Koprowski
Journal: J Exp Med Date: 1974-11-01 Impact factor: 14.307

13 in total

Review 1. Comparative map for mice and humans.

Authors: J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal: Mamm Genome Date: 1992 Impact factor: 2.957

Review 2. Comparative map for mice and humans.

Authors: J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal: Mamm Genome Date: 1991 Impact factor: 2.957

3. Loss of mouse chromosomes in somatic cell hybrids between HT-1080 human fibrosarcoma cells and mouse peritioneal macrophages.

Authors: C M Croce
Journal: Proc Natl Acad Sci U S A Date: 1976-09 Impact factor: 11.205

10. Detection of active heteropolymeric beta-glucuronidase in hybrids between mouse cells and human fibroblasts with beta-glucuronidase deficiency.

Authors: C J Chern
Journal: Proc Natl Acad Sci U S A Date: 1977-07 Impact factor: 11.205