Literature DB >> 9415161

Comparative protein modeling by satisfaction of spatial restraints.

A Sali1.   

Abstract

Approximately one third of known protein sequences are related to at least one known protein structure. As a result, an order of magnitude more sequences can be modeled by comparative modeling than there are experimentally determined protein structures. A large fraction of these models has an accuracy approaching that of a low resolution X-ray structure or a medium resolution nuclear magnetic resonance structure. The number of applications where homology modeling has been proven useful is growing rapidly.

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Year:  1995        PMID： 9415161     DOI： 10.1016/s1357-4310(95)91170-7

Source DB:  PubMed          Journal:  Mol Med Today        ISSN： 1357-4310


  85 in total

1.  Alteration of pore properties of Escherichia coli OmpF induced by mutation of key residues in anti-loop 3 region.

Authors:  Jérôme Bredin; Nathalie Saint; Monique Malléa; Emmanuelle Dé; Gérard Molle; Jean-Marie Pagès; Valérie Simonet
Journal:  Biochem J       Date:  2002-05-01       Impact factor: 3.857

2.  The structure of the inter-SH2 domain of class IA phosphoinositide 3-kinase determined by site-directed spin labeling EPR and homology modeling.

Authors:  Zheng Fu; Eliah Aronoff-Spencer; Jonathan M Backer; Gary J Gerfen
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-10       Impact factor: 11.205

3.  Selective refinement and selection of near-native models in protein structure prediction.

Authors:  Jiong Zhang; Bogdan Barz; Jingfen Zhang; Dong Xu; Ioan Kosztin
Journal:  Proteins       Date:  2015-08-12

4.  High-throughput computational and experimental techniques in structural genomics.

Authors:  Mark R Chance; Andras Fiser; Andrej Sali; Ursula Pieper; Narayanan Eswar; Guiping Xu; J Eduardo Fajardo; Thirumuruhan Radhakannan; Nebojsa Marinkovic
Journal:  Genome Res       Date:  2004-10       Impact factor: 9.043

5.  Lopap, a prothrombin activator from Lonomia obliqua belonging to the lipocalin family: recombinant production, biochemical characterization and structure-function insights.

Authors:  Cleyson Valença Reis; Sonia Aparecida Andrade; Oscar Henrique Pereira Ramos; Celso Raul Romero Ramos; Paulo Lee Ho; Isabel de Fátima Correia Batista; Ana Marisa Chudzinski-Tavassi
Journal:  Biochem J       Date:  2006-09-01       Impact factor: 3.857

6.  Sulfated polymannuroguluronate inhibits Tat-induced SLK cell adhesion via a novel binding site, a KKR spatial triad.

Authors:  Yan-lin Wu; Jing Ai; Jing-ming Zhao; Bing Xiong; Xiao-jie Xin; Mei-yu Geng; Xian-liang Xin; Han-dong Jiang
Journal:  Acta Pharmacol Sin       Date:  2011-04-18       Impact factor: 6.150

7.  Characterization of a novel water pocket inside the human Cx26 hemichannel structure.

Authors:  Raul Araya-Secchi; Tomas Perez-Acle; Seung-Gu Kang; Tien Huynh; Alejandro Bernardin; Yerko Escalona; Jose-Antonio Garate; Agustin D Martínez; Isaac E García; Juan C Sáez; Ruhong Zhou
Journal:  Biophys J       Date:  2014-08-05       Impact factor: 4.033

8.  Analysis of the complement sensitivity of oral treponemes and the potential influence of FH binding, FH cleavage and dentilisin activity on the pathogenesis of periodontal disease.

Authors:  D P Miller; J V McDowell; J K Bell; M P Goetting-Minesky; J C Fenno; R T Marconi
Journal:  Mol Oral Microbiol       Date:  2014-06-03       Impact factor: 3.563

9.  Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo.

Authors:  Eva Maria Novoa; Noelia Camacho; Anna Tor; Barrie Wilkinson; Steven Moss; Patricia Marín-García; Isabel G Azcárate; José M Bautista; Adam C Mirando; Christopher S Francklyn; Sònia Varon; Miriam Royo; Alfred Cortés; Lluís Ribas de Pouplana
Journal:  Proc Natl Acad Sci U S A       Date:  2014-12-08       Impact factor: 11.205

10.  Functional characterization of nonsynonymous single nucleotide polymorphisms in the human organic anion transporter 4 (hOAT4).

Authors:  Fanfan Zhou; Ling Zhu; Pei H Cui; W Bret Church; Michael Murray
Journal:  Br J Pharmacol       Date:  2009-12-10       Impact factor: 8.739
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