Literature DB >> 9406181

Degradative covalent reactions important to protein stability.

D B Volkin1, H Mach, C R Middaugh.   

Abstract

Commonly observed chemical modifications that occur in proteins during their in vitro purification, storage, and handling are discussed. Covalent modifications described include deamidation and isoaspartate formation, cleavage of peptide bonds at aspartic acid residues, cystine destruction and thiol-disulfide interchange, oxidation of cysteine and methionine residues, and the glycation and carbamylation of amino groups.

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Year:  1997        PMID： 9406181     DOI： 10.1007/BF02752255

Source DB:  PubMed          Journal:  Mol Biotechnol        ISSN： 1073-6085            Impact factor:   2.695


  84 in total

Review 1.  Enzymatic catalysis in anhydrous organic solvents.

Authors:  A M Klibanov
Journal:  Trends Biochem Sci       Date:  1989-04       Impact factor: 13.807

2.  Preferential release of aspartic acid during the hydrolysis of proteins.

Authors:  S M PARTRIDGE; H F DAVIS
Journal:  Nature       Date:  1950-01-14       Impact factor: 49.962

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Authors:  G R Stark
Journal:  Biochemistry       Date:  1965-06       Impact factor: 3.162

Review 4.  Analysis of processes causing thermal inactivation of enzymes.

Authors:  T J Ahern; A M Klibanov
Journal:  Methods Biochem Anal       Date:  1988

5.  Redox control of enzyme activities by thiol/disulfide exchange.

Authors:  H F Gilbert
Journal:  Methods Enzymol       Date:  1984       Impact factor: 1.600

6.  Influence of the location of tryptophanyl residues in proteins on their photosensitivity.

Authors:  C Pigault; D Gerard
Journal:  Photochem Photobiol       Date:  1984-09       Impact factor: 3.421

7.  Immunochemical approach to characterize advanced glycation end products of the Maillard reaction. Evidence for the presence of a common structure.

Authors:  S Horiuchi; N Araki; Y Morino
Journal:  J Biol Chem       Date:  1991-04-25       Impact factor: 5.157

8.  Methionine oxidation and inactivation of alpha 1-proteinase inhibitor by Cu2+ and glucose.

Authors:  P K Hall; R C Roberts
Journal:  Biochim Biophys Acta       Date:  1992-06-24

9.  Thermal destruction processes in proteins involving cystine residues.

Authors:  D B Volkin; A M Klibanov
Journal:  J Biol Chem       Date:  1987-03-05       Impact factor: 5.157

10.  Sequence-specific deamidation: isolation and biochemical characterization of succinimide intermediates of recombinant hirudin.

Authors:  R Bischoff; P Lepage; M Jaquinod; G Cauet; M Acker-Klein; D Clesse; M Laporte; A Bayol; A Van Dorsselaer; C Roitsch
Journal:  Biochemistry       Date:  1993-01-19       Impact factor: 3.162
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  25 in total

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2.  Selective cleavage of isoaspartyl peptide bonds by hydroxylamine after methyltransferase priming.

Authors:  Jeff X Zhu; Dana W Aswad
Journal:  Anal Biochem       Date:  2007-02-22       Impact factor: 3.365

3.  Whole proteome analysis of post-translational modifications: applications of mass-spectrometry for proteogenomic annotation.

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Review 4.  High-throughput biophysical analysis of protein therapeutics to examine interrelationships between aggregate formation and conformational stability.

Authors:  Rajoshi Chaudhuri; Yuan Cheng; C Russell Middaugh; David B Volkin
Journal:  AAPS J       Date:  2013-10-31       Impact factor: 4.009

Review 5.  Glycosylation of therapeutic proteins: an effective strategy to optimize efficacy.

Authors:  Ricardo J Solá; Kai Griebenow
Journal:  BioDrugs       Date:  2010-02-01       Impact factor: 5.807

6.  Method for Efficient Refolding and Purification of Chemoreceptor Ligand Binding Domain.

Authors:  Mayra A Machuca; Anna Roujeinikova
Journal:  J Vis Exp       Date:  2017-12-12       Impact factor: 1.355

7.  Probing residue-specific interactions in the stabilization of proteins using high-resolution NMR: a study of disulfide bond compensation.

Authors:  Andria L Skinner; Jennifer S Laurence
Journal:  J Pharm Sci       Date:  2010-06       Impact factor: 3.534

8.  Isoaspartyl protein damage and repair in mouse retina.

Authors:  Zhenxia Qin; Jing Yang; Henry J Klassen; Dana W Aswad
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-03-13       Impact factor: 4.799

Review 9.  Effects of glycosylation on the stability of protein pharmaceuticals.

Authors:  Ricardo J Solá; Kai Griebenow
Journal:  J Pharm Sci       Date:  2009-04       Impact factor: 3.534

10.  Theoretical study on isomerization and peptide bond cleavage at aspartic residue.

Authors:  Wichien Sang-aroon; Vithaya Ruangpornvisuti
Journal:  J Mol Model       Date:  2013-06-11       Impact factor: 1.810
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