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Literature DB >> 9406174

Cardiomyopathies and mitochondrial DNA mutations.

Abstract

Our former studies concerning mitochondrial DNA mutations were reviewed in this article. A 7.4 kb deletion between the D-loop and ATPase 6 genes was detected in myocardial tissue obtained at autopsy from patients with myocardial infarction, diabetes mellitus and also patients treated with adriamycin. A case with diabetes mellitus and hypertrophic cardiomyopathy is demonstrated which revealed a point mutation from adenine to guanine at position 3243 within tRNA Leu(UUR).

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 1997 PMID： 9406174

Source DB: PubMed Journal: Mol Cell Biochem ISSN： 0300-8177 Impact factor: 3.396

19 in total

1. Point mutations in mitochondrial DNA in patients with hypertrophic cardiomyopathy.

Authors: T Obayashi; K Hattori; S Sugiyama; M Tanaka; T Tanaka; S Itoyama; H Deguchi; K Kawamura; Y Koga; H Toshima
Journal: Am Heart J Date: 1992-11 Impact factor: 4.749

2. A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies.

Authors: Y Goto; I Nonaka; S Horai
Journal: Nature Date: 1990-12-13 Impact factor: 49.962

3. Mitochondrial DNA mutations and survival rate.

Authors: T Ozawa; K Katsumata; M Hayakawa; M Yoneda; M Tanaka; S Sugiyama
Journal: Lancet Date: 1995-01-21 Impact factor: 79.321

4. Sequence and organization of the human mitochondrial genome.

Authors: S Anderson; A T Bankier; B G Barrell; M H de Bruijn; A R Coulson; J Drouin; I C Eperon; D P Nierlich; B A Roe; F Sanger; P H Schreier; A J Smith; R Staden; I G Young
Journal: Nature Date: 1981-04-09 Impact factor: 49.962

5. Direct sequencing of deleted mitochondrial DNA in myopathic patients.

Authors: M Tanaka; W Sato; K Ohno; T Yamamoto; T Ozawa
Journal: Biochem Biophys Res Commun Date: 1989-10-16 Impact factor: 3.575

6. Multiple mitochondrial DNA deletions exist in cardiomyocytes of patients with hypertrophic or dilated cardiomyopathy.

Authors: T Ozawa; M Tanaka; S Sugiyama; K Hattori; T Ito; K Ohno; A Takahashi; W Sato; G Takada; B Mayumi
Journal: Biochem Biophys Res Commun Date: 1990-07-31 Impact factor: 3.575

7. Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts.

Authors: M Hayakawa; K Hattori; S Sugiyama; T Ozawa
Journal: Biochem Biophys Res Commun Date: 1992-12-15 Impact factor: 3.575

8. Mitochondrial DNA deletion in human myocardium.

Authors: N Takeda; A Tanamura; T Iwai; I Nakamura; M Kato; T Ohkubo; K Noma
Journal: Mol Cell Biochem Date: 1993-02-17 Impact factor: 3.396

9. Mitochondrial diabetes mellitus: prevalence and clinical characterization of diabetes due to mitochondrial tRNA(Leu(UUR)) gene mutation in Japanese patients.

Authors: H Katagiri; T Asano; H Ishihara; K Inukai; M Anai; T Yamanouchi; K Tsukuda; M Kikuchi; H Kitaoka; N Ohsawa
Journal: Diabetologia Date: 1994-05 Impact factor: 10.122