| Literature DB >> 9405347 |
E Huala1, P W Oeller, E Liscum, I S Han, E Larsen, W R Briggs.
Abstract
The NPH1 (nonphototropic hypocotyl 1) gene encodes an essential component acting very early in the signal-transduction chain for phototropism. Arabidopsis NPH1 contains a serine-threonine kinase domain and LOV1 and LOV2 repeats that share similarity (36 to 56 percent) with Halobacterium salinarium Bat, Azotobacter vinelandii NIFL, Neurospora crassa White Collar-1, Escherichia coli Aer, and the Eag family of potassium-channel proteins from Drosophila and mammals. Sequence similarity with a known (NIFL) and a suspected (Aer) flavoprotein suggests that NPH1 LOV1 and LOV2 may be flavin-binding domains that regulate kinase activity in response to blue light-induced redox changes.Entities:
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Year: 1997 PMID： 9405347 DOI： 10.1126/science.278.5346.2120
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728