Literature DB >> 9398067

Gene therapy.

M A Kay1, D Liu, P M Hoogerbrugge.   

Abstract

In recent years, there have been a number of technological breakthroughs that have allowed for clinical trials in gene therapy to be initiated. In combination with the genome initiative, the potential for new therapeutics is limitless. Although an enormous amount of information has been obtained in a relatively short period of time, gene therapy is not yet ready for wide-scale practice. Some of the successes and obstacles that remain are summarized in this report.

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Year:  1997        PMID： 9398067      PMCID： PMC34169          DOI： 10.1073/pnas.94.24.12744

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  32 in total

1.  Long-term expression of human adenosine deaminase in rhesus monkeys transplanted with retrovirus-infected bone-marrow cells.

Authors:  V W van Beusechem; A Kukler; P J Heidt; D Valerio
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-15       Impact factor: 11.205

2.  Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

Authors:  P L Felgner; T R Gadek; M Holm; R Roman; H W Chan; M Wenz; J P Northrop; G M Ringold; M Danielsen
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

3.  Gene therapy in the United States: a five-year status report.

Authors:  G Ross; R Erickson; D Knorr; A G Motulsky; R Parkman; J Samulski; S E Straus; B R Smith
Journal:  Hum Gene Ther       Date:  1996-09-10       Impact factor: 5.695

4.  A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal.

Authors:  R J Parks; L Chen; M Anton; U Sankar; M A Rudnicki; F L Graham
Journal:  Proc Natl Acad Sci U S A       Date:  1996-11-26       Impact factor: 11.205

5.  Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations.

Authors:  J H Felgner; R Kumar; C N Sridhar; C J Wheeler; Y J Tsai; R Border; P Ramsey; M Martin; P L Felgner
Journal:  J Biol Chem       Date:  1994-01-28       Impact factor: 5.157

6.  Gene transfer into hematopoietic stem cells: long-term maintenance of in vitro activated progenitors without marrow ablation.

Authors:  D Bienzle; A C Abrams-Ogg; S A Kruth; J Ackland-Snow; R F Carter; J E Dick; R M Jacobs; S Kamel-Reid; I D Dubé
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-04       Impact factor: 11.205

7.  A novel cationic liposome reagent for efficient transfection of mammalian cells.

Authors:  X Gao; L Huang
Journal:  Biochem Biophys Res Commun       Date:  1991-08-30       Impact factor: 3.575

8.  Gene-marking to trace origin of relapse after autologous bone-marrow transplantation.

Authors:  M K Brenner; D R Rill; R C Moen; R A Krance; J Mirro; W F Anderson; J N Ihle
Journal:  Lancet       Date:  1993-01-09       Impact factor: 79.321

9.  Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.

Authors:  S Ishibashi; M S Brown; J L Goldstein; R D Gerard; R E Hammer; J Herz
Journal:  J Clin Invest       Date:  1993-08       Impact factor: 14.808

10.  In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs.

Authors:  M A Kay; C N Landen; S R Rothenberg; L A Taylor; F Leland; S Wiehle; B Fang; D Bellinger; M Finegold; A R Thompson
Journal:  Proc Natl Acad Sci U S A       Date:  1994-03-15       Impact factor: 11.205
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  18 in total

Review 1.  Gene delivery from replication-selective viruses: arming guided missiles in the war against cancer.

Authors:  T Hermiston
Journal:  J Clin Invest       Date:  2000-05       Impact factor: 14.808

2.  The 17 nucleotides downstream from the env gene stop codon are important for murine leukemia virus packaging.

Authors:  S S Yu; J M Kim; S Kim
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

3.  Prevalence of neutralizing antibodies to adenoviral serotypes 5 and 35 in the adult populations of The Gambia, South Africa, and the United States.

Authors:  Edward Nwanegbo; Eftyhia Vardas; Wentao Gao; Hilton Whittle; Huijie Sun; David Rowe; Paul D Robbins; Andrea Gambotto
Journal:  Clin Diagn Lab Immunol       Date:  2004-03

4.  Considerations for the treatment of infantile neuronal ceroid lipofuscinosis (infantile Batten disease).

Authors:  Mark S Sands
Journal:  J Child Neurol       Date:  2013-09       Impact factor: 1.987

5.  Effects of moisture content on the storage stability of dried lipoplex formulations.

Authors:  Jinxiang Yu; Thomas J Anchordoquy
Journal:  J Pharm Sci       Date:  2009-09       Impact factor: 3.534

6.  Synergistic effects of surfactants and sugars on lipoplex stability during freeze-drying and rehydration.

Authors:  Jinxiang Yu; Thomas J Anchordoquy
Journal:  J Pharm Sci       Date:  2009-09       Impact factor: 3.534

7.  Biodegradable polyester, poly[alpha-(4-aminobutyl)-L-glycolic acid], as a non-toxic gene carrier.

Authors:  Y B Lim; S O Han; H U Kong; Y Lee; J S Park; B Jeong; S W Kim
Journal:  Pharm Res       Date:  2000-07       Impact factor: 4.200

8.  Recombinant, replication-defective adenovirus gene transfer vectors induce cell cycle dysregulation and inappropriate expression of cyclin proteins.

Authors:  R P Wersto; E R Rosenthal; P K Seth; N T Eissa; R E Donahue
Journal:  J Virol       Date:  1998-12       Impact factor: 5.103

9.  Gene and cell therapy for muscle regeneration.

Authors:  Roberta Sessa Stilhano; Leonardo Martins; Sheila Jean McNeill Ingham; João Bosco Pesquero; Johnny Huard
Journal:  Curr Rev Musculoskelet Med       Date:  2015-06

10.  Exploitation of nucleic acid packaging signals to generate a novel influenza virus-based vector stably expressing two foreign genes.

Authors:  Tokiko Watanabe; Shinji Watanabe; Takeshi Noda; Yutaka Fujii; Yoshihiro Kawaoka
Journal:  J Virol       Date:  2003-10       Impact factor: 5.103
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