| Literature DB >> 25899573 |
Roberta Sessa Stilhano1, Leonardo Martins1, Sheila Jean McNeill Ingham2, João Bosco Pesquero1, Johnny Huard3.
Abstract
Skeletal muscle injury and healing are multifactorial processes, involving three steps of healing: (1) degeneration and inflammation, (2) regeneration, and (3) fibrosis. Fibrous tissue hinders the muscle's complete recovery and current therapies fail in achieving total muscle recovery. Gene and cell therapy (or both) are potential future treatments for severe muscular injuries. Stem cells' properties associated with growth factors or/and cytokines can improve muscle healing and permit long-term recovery.Entities:
Year: 2015 PMID: 25899573 PMCID: PMC4596170 DOI: 10.1007/s12178-015-9268-9
Source DB: PubMed Journal: Curr Rev Musculoskelet Med ISSN: 1935-9748