Literature DB >> 9395689

A comparative survey of leguminous plants as sources of the isoflavones, genistein and daidzein: implications for human nutrition and health.

P B Kaufman1, J A Duke, H Brielmann, J Boik, J E Hoyt.   

Abstract

Over 80 taxa of mostly agriculturally important legumes were surveyed as sources of the metabolites, genistein and daidzein. Remarkably high concentrations (over 2 g.kg-1 dry weight) of the anticancer metabolite, genistein, were found in the leaves of Psoralea corylifolia (Indian bread root). All other legumes, with the exception of fermented soybean miso, had genistein levels < 400 mg.kg-1 dry weight. Concentrations of over 1 g.kg-1 dry weight and 0.95 g.kg-1 dry weight of the anticancer metabolite, daidzein, were found in the stems of the fava bean (Vicia faba) and roots of kudzu vine (Pueraria lobata), respectively. From this survey, our results indicate that the legumes, lupine (Lupinus spp.), fava bean, (Vicia faba), soybeans (Glycine max), kudzu (Pueraria lobata), and psoralea (Psoralea corylifolia), are excellent food sources for both genistein and daidzein. Miso, a fermented soybean product, is also a rich source of both isoflavones.

Entities:  

Keywords:  Non-programmatic

Mesh:

Substances:

Year:  1997        PMID: 9395689     DOI: 10.1089/acm.1997.3.7

Source DB:  PubMed          Journal:  J Altern Complement Med        ISSN: 1075-5535            Impact factor:   2.579


  47 in total

1.  Purification and characterization of a novel bacteriocin produced by Enterococcus faecalis strain RJ-11.

Authors:  Yukio Yamamoto; Yoshikazu Togawa; Makoto Shimosaka; Mitsuo Okazaki
Journal:  Appl Environ Microbiol       Date:  2003-10       Impact factor: 4.792

2.  Regulation of the neuroendocrine axis in male rats by soy-based diets is independent of age and due specifically to isoflavone action†.

Authors:  Bamidele O Jeminiwa; Rachel M Knight; Tim D Braden; Crisanta Cruz-Espindola; Dawn M Boothe; Benson T Akingbemi
Journal:  Biol Reprod       Date:  2020-10-05       Impact factor: 4.285

3.  Can the chemotherapeutic agents perform anticancer activity through miRNA expression regulation? Proposing a new hypothesis [corrected].

Authors:  Chiranjib Chakraborty; C George Priya Doss; Renu Sarin; Minna J Hsu; Govindasamy Agoramoorthy
Journal:  Protoplasma       Date:  2015-02-20       Impact factor: 3.356

4.  Characterization of isoflavone synthase gene from Psoralea corylifolia: a medicinal plant.

Authors:  Prashant Misra; Ashutosh Pandey; Shri Krishna Tewari; Pravendra Nath; Prabodh Kumar Trivedi
Journal:  Plant Cell Rep       Date:  2010-05-01       Impact factor: 4.570

Review 5.  Novel anti-HIV therapeutics targeting chemokine receptors and actin regulatory pathways.

Authors:  Mark Spear; Jia Guo; Yuntao Wu
Journal:  Immunol Rev       Date:  2013-11       Impact factor: 12.988

Review 6.  Impact of Epigenetic Dietary Components on Cancer through Histone Modifications.

Authors:  Yifeng Gao; Trygve O Tollefsbol
Journal:  Curr Med Chem       Date:  2015       Impact factor: 4.530

7.  Analysis of isoflavone contents in vegetable soybeans.

Authors:  T Mebrahtu; A Mohamed; C Y Wang; T Andebrhan
Journal:  Plant Foods Hum Nutr       Date:  2004       Impact factor: 3.921

8.  Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4).

Authors:  Mykhaylo S Frasinyuk; Wen Zhang; Przemyslaw Wyrebek; Tianxin Yu; Xuehe Xu; Vitaliy M Sviripa; Svitlana P Bondarenko; Yanqi Xie; Huy X Ngo; Andrew J Morris; James L Mohler; Michael V Fiandalo; David S Watt; Chunming Liu
Journal:  Org Biomol Chem       Date:  2017-09-20       Impact factor: 3.876

9.  Genistein-3'-sulfonic acid dihydrate.

Authors:  Chang-Peng Zhang; Hao Ni; Hai-Yan Tu; Yong-Rong Xie; Rui-Qing Yang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-04-30

10.  Isolation of radiolabeled isoflavones from kudzu (Pueraria lobata) root cultures.

Authors:  Adam Reppert; Gad G Yousef; Randy B Rogers; Mary Ann Lila
Journal:  J Agric Food Chem       Date:  2008-08-09       Impact factor: 5.279

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.